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CATH Superfamily 3.30.810.10

2-Layer Sandwich

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
2-Layer Sandwich
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Phosphatidylinositol 4-phosphate 5-kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1-phosphatidylinositol-4-phosphate 5-kinase. [EC: 2.7.1.68]
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.
  • This enzyme can also phosphorylate PtdIns3P in the 4-position, and PtdIns, PtdIns3P and PtdIns(3,4)P(2) in the 5-position in vitro, but to a lesser extent.
  • The last of these reactions occurs in vivo and is physiologically relevant.
 24 A0A178W750 A0A178W750 A0A178W978 A0A178W978 A0A178WK69 A0A178WK69 A0A384KKN2 A0A384KKN2 A0A384KKN2 O48709
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