The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
AP2/ERF domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: AP2-like ethylene-responsive transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
18 A8MQS2 (/ISS) F4IIR3 (/ISS) F4IIR3 (/ISS) F4KGW7 (/ISS) P47927 (/ISS) P47927 (/ISS) Q1PFE1 (/ISS) Q38914 (/ISS) Q5YGP7 (/ISS) Q5YGP8 (/ISS)
(8 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 Q2TQ34 (/IPI) Q2TQ34 (/IPI) Q5YGP7 (/IPI) Q5YGP8 (/IPI) Q84TB5 (/IPI) Q84TB5 (/IPI) Q84TB5 (/IPI) Q84TB5 (/IPI) Q8H443 (/IPI) Q8H443 (/IPI)
(2 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 A0A0N7KJT8 (/IDA) A0A0N7KJT8 (/IDA) A8MQS2 (/IDA) B8AVJ9 (/IDA) B8AVJ9 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
4 A0A0N7KJT8 (/IDA) A0A0N7KJT8 (/IDA) B8AVJ9 (/IDA) B8AVJ9 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 A8MQS2 (/IPI) Q94AN4 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 Q38914 (/IDA) Q6X5Y6 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 P47927 (/TAS) P47927 (/TAS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 F4KGW7 (/IPI) Q38914 (/IPI)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 A8MQS2 (/IDA)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
1 Q6X5Y6 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 A8MQS2 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 F4KGW7 (/IPI)

There are 55 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of flower development GO:0009909
Any process that modulates the frequency, rate or extent of flower development.
14 A0A0N7KJT8 (/IMP) A0A0N7KJT8 (/IMP) A0A0N7KMH0 (/IMP) A0A0N7KMH0 (/IMP) B8AVJ9 (/IMP) B8AVJ9 (/IMP) Q2TQ34 (/IMP) Q2TQ34 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP)
(4 more)
Regulation of seed development GO:0080050
Any process that modulates the frequency, rate or extent of seed development.
12 A0A0N7KJT8 (/IMP) A0A0N7KJT8 (/IMP) A0A0N7KMH0 (/IMP) A0A0N7KMH0 (/IMP) B8AVJ9 (/IMP) B8AVJ9 (/IMP) Q2TQ34 (/IMP) Q2TQ34 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP)
(2 more)
Vegetative to reproductive phase transition of meristem GO:0010228
The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
8 F4IIR3 (/IMP) F4IIR3 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP) Q8H443 (/IMP) Q8H443 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6 Q84TB5 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP) Q84TB5 (/IMP) Q8H443 (/IMP) Q8H443 (/IMP)
Seed development GO:0048316
The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
4 E7EAV8 (/IMP) E7EAV8 (/IMP) P47927 (/IMP) P47927 (/IMP)
Regulation of floral organ abscission GO:0060860
Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.
4 A0A0N7KJT8 (/IMP) A0A0N7KJT8 (/IMP) B8AVJ9 (/IMP) B8AVJ9 (/IMP)
Seed abscission GO:0097548
The controlled shedding of a seed.
4 A0A0N7KJT8 (/IMP) A0A0N7KJT8 (/IMP) B8AVJ9 (/IMP) B8AVJ9 (/IMP)
Lateral root formation GO:0010311
The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.
3 F4KGW7 (/IGI) Q6J9N8 (/IGI) Q6PQQ3 (/IGI)
Maintenance of shoot apical meristem identity GO:0010492
The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
3 F4KGW7 (/IGI) Q38914 (/IGI) Q6J9N8 (/IGI)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
3 F4KGW7 (/IGI) Q5YGP7 (/IGI) Q5YGP8 (/IGI)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
3 Q5YGP7 (/IMP) Q5YGP8 (/IMP) Q6PQQ3 (/IMP)
Phyllotactic patterning GO:0060771
The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.
3 F4KGW7 (/IGI) Q6J9N8 (/IGI) Q6PQQ3 (/IGI)
Leaf phyllotactic patterning GO:0060772
The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.
3 F4KGW7 (/IGI) Q6J9N8 (/IGI) Q6PQQ3 (/IGI)
Auxin mediated signaling pathway involved in phyllotactic patterning GO:0060774
The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.
3 F4KGW7 (/IGI) Q6J9N8 (/IGI) Q6PQQ3 (/IGI)
Positive regulation of cutin biosynthetic process GO:1901959
Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.
3 A8MQS2 (/IGI) Q6X5Y6 (/IGI) Q94AN4 (/IGI)
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
2 Q5YGP7 (/IDA) Q5YGP8 (/IDA)
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
2 Q5YGP7 (/IMP) Q5YGP8 (/IMP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 A0A0N7KJT8 (/IEP) A0A0N7KJT8 (/IEP)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
2 P47927 (/TAS) P47927 (/TAS)
Meristem maintenance GO:0010073
Any process involved in maintaining the identity, size and shape of a meristem.
2 P47927 (/IMP) P47927 (/IMP)
Specification of floral organ identity GO:0010093
The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
2 P47927 (/IMP) P47927 (/IMP)
Floral organ abscission GO:0010227
The controlled shedding of floral organs.
2 E7EAV8 (/IMP) E7EAV8 (/IMP)
Root meristem growth GO:0010449
The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.
2 Q5YGP7 (/IGI) Q5YGP8 (/IGI)
Regulation of starch biosynthetic process GO:0010581
An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.
2 Q2TQ34 (/IMP) Q2TQ34 (/IMP)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
2 Q5YGP7 (/IMP) Q5YGP8 (/IMP)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
2 A8MQS2 (/IGI) Q94AN4 (/IGI)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
2 A8MQS2 (/IMP) Q94AN4 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q2TQ34 (/IMP) Q2TQ34 (/IMP)
Flower structural organization GO:0048461
The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.
2 E7EAV8 (/IMP) E7EAV8 (/IMP)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
2 P47927 (/IGI) P47927 (/IGI)
Floral organ senescence GO:0080187
An organ senescence that has as a participant a floral organ.
2 E7EAV8 (/IMP) E7EAV8 (/IMP)
Regulation of endosperm development GO:2000014
Any process that modulates the frequency, rate or extent of endosperm development.
2 Q2TQ34 (/IMP) Q2TQ34 (/IMP)
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
1 Q6X5Y6 (/IMP)
Regulation of glycolytic process GO:0006110
Any process that modulates the frequency, rate or extent of glycolysis.
1 Q6X5Y6 (/IMP)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 Q6X5Y6 (/IMP)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
1 Q6X5Y6 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
1 Q94AN4 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q94AN4 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q94AN4 (/IMP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
1 Q6X5Y6 (/IEP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
1 Q6PQQ3 (/IMP)
Seed germination GO:0009845
The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
1 Q6PQQ3 (/IMP)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
1 F4KGW7 (/IMP)
Meristem maintenance GO:0010073
Any process involved in maintaining the identity, size and shape of a meristem.
1 Q5YGP7 (/IGI)
Regulation of floral meristem growth GO:0010080
Any process involved in maintaining the size and shape of a floral meristem.
1 F4KGW7 (/IMP)
Negative regulation of seed germination GO:0010187
Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.
1 Q94AN4 (/IMP)
Triglyceride biosynthetic process GO:0019432
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
1 Q6X5Y6 (/IMP)
Glucosinolate metabolic process GO:0019760
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
1 Q38914 (/IMP)
Organ growth GO:0035265
The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.
1 F4KGW7 (/IMP)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
1 Q94AN4 (/IMP)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
1 Q6PQQ3 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q38914 (/IMP)
Adventitious root development GO:0048830
The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
1 Q84Z02 (/IMP)
Negative regulation of cytokinin-activated signaling pathway GO:0080037
Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.
1 Q84Z02 (/IMP)
Positive regulation of wax biosynthetic process GO:1904278
Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.
1 A8MQS2 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 A0A0N7KJT8 (/IDA) A0A0N7KJT8 (/IDA) A8MQS2 (/IDA) B8AVJ9 (/IDA) B8AVJ9 (/IDA) Q5YGP8 (/IDA) Q6PQQ3 (/IDA) Q8H443 (/IDA) Q8H443 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
4 A0A0N7KJT8 (/IDA) A0A0N7KJT8 (/IDA) B8AVJ9 (/IDA) B8AVJ9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P47927 (/ISS) P47927 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5YGP7 (/NAS)