The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: CUGBP Elav-like family member 4 isoform 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
23 M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRZ0 (/IDA) M9MRZ0 (/IDA)
(13 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
23 M9MRT4 (/ISS) M9MRT4 (/ISS) M9MRT4 (/ISS) M9MRT4 (/ISS) M9MRU5 (/ISS) M9MRU5 (/ISS) M9MRU5 (/ISS) M9MRU5 (/ISS) M9MRZ0 (/ISS) M9MRZ0 (/ISS)
(13 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
23 M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRZ0 (/IDA) M9MRZ0 (/IDA)
(13 more)
BRE binding GO:0042835
Interacting selectively and non-covalently with the RNA element BRE (Bruno response element).
18 Q7TSY6 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS) Q9BZC1 (/ISS)
(8 more)
Translation repressor activity, mRNA regulatory element binding GO:0000900
Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
17 Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS)
(7 more)
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
17 Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA)
(7 more)
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
9 Q5SZQ8 (/NAS) Q5SZQ8 (/NAS) Q5SZQ8 (/NAS) Q5SZQ8 (/NAS) Q5SZQ8 (/NAS) Q8N6W0 (/NAS) Q8N6W0 (/NAS) Q8N6W0 (/NAS) Q8N6W0 (/NAS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
5 Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q8CIN6 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q8CIN6 (/ISO)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
1 Q7TSY6 (/IDA)
Pre-mRNA binding GO:0036002
Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
1 Q7TSY6 (/ISO)
7SK snRNA binding GO:0097322
Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA).
1 Q8CIN6 (/IPI)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of mRNA splicing, via spliceosome GO:0048026
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
30 Q08E07 (/ISS) Q08E07 (/ISS) Q08E07 (/ISS) Q4R535 (/ISS) Q4R535 (/ISS) Q4R535 (/ISS) Q5NVC8 (/ISS) Q5NVC8 (/ISS) Q5NVC8 (/ISS) Q5NVC8 (/ISS)
(20 more)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
26 Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q8N6W0 (/IDA) Q8N6W0 (/IDA) Q8N6W0 (/IDA) Q8N6W0 (/IDA) Q9BZC1 (/IDA)
(16 more)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
23 M9MRT4 (/ISA) M9MRT4 (/ISA) M9MRT4 (/ISA) M9MRT4 (/ISA) M9MRU5 (/ISA) M9MRU5 (/ISA) M9MRU5 (/ISA) M9MRU5 (/ISA) M9MRZ0 (/ISA) M9MRZ0 (/ISA)
(13 more)
Positive regulation of mRNA splicing, via spliceosome GO:0048026
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
22 Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA)
(12 more)
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
17 Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA)
(7 more)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
17 Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS)
(7 more)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
17 Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS) Q9BZC1 (/NAS)
(7 more)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
5 Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP) Q5SZQ8 (/IMP)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
4 D3Z4T1 (/ISO) D3Z580 (/ISO) Q7TSY6 (/ISO) Q8CIN6 (/ISO)
Positive regulation of mRNA splicing, via spliceosome GO:0048026
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
2 Q7TSY6 (/ISO) Q8CIN6 (/ISO)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q7TSY6 (/IMP)
MRNA splice site selection GO:0006376
Selection of a splice site by components of the assembling spliceosome.
1 Q7TSY6 (/IDA)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q8CIN6 (/IMP)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
1 Q8CIN6 (/ISO)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
1 Q8CIN6 (/IMP)
Nuclear body organization GO:0030575
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q8CIN6 (/IMP)
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
1 Q7TSY6 (/IMP)
Negative regulation of excitatory postsynaptic potential GO:0090394
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
1 Q7TSY6 (/IMP)
NcRNA transcription GO:0098781
The transcription of non (protein) coding RNA from a DNA template.
1 Q8CIN6 (/IMP)
Regulation of retina development in camera-type eye GO:1902866
Any process that modulates the frequency, rate or extent of retina development in camera-type eye.
1 Q7TSY6 (/IEP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
24 Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q7TSY6 (/IDA) Q8CIN6 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA) Q9BZC1 (/IDA)
(14 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
23 M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRT4 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRU5 (/IDA) M9MRZ0 (/IDA) M9MRZ0 (/IDA)
(13 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q5SZQ8 (/IDA) Q7TSY6 (/IDA) Q8CIN6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q7TSY6 (/ISS) Q8N6W0 (/ISS) Q8N6W0 (/ISS) Q8N6W0 (/ISS) Q8N6W0 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q7TSY6 (/ISO) Q8CIN6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8CIN6 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q8CIN6 (/IDA)