The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 311: polyadenylate-binding protein 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
23 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS)
(13 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI) Q86U42 (/IPI)
(9 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
18 Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA) Q86U42 (/HDA)
(8 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
4 Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
2 Q6TY21 (/IDA) Q804A5 (/IDA)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
1 Q8CCS6 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q804A5 (/IPI)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
1 Q28165 (/IDA)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
1 Q8CCS6 (/ISO)
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
1 Q8CCS6 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
23 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS)
(13 more)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
23 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS)
(13 more)
Positive regulation of polynucleotide adenylyltransferase activity GO:1904247
Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.
23 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS) Q86U42 (/ISS)
(13 more)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
18 Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP) Q86U42 (/IMP)
(8 more)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
Modification by virus of host mRNA processing GO:0046778
Any viral process that interferes with the processing of mRNA in the host cell.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
4 Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
1 Q8CCS6 (/IMP)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
1 Q8CCS6 (/TAS)
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
1 Q8CCS6 (/ISO)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q8CCS6 (/IMP)
Positive regulation of polynucleotide adenylyltransferase activity GO:1904247
Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.
1 Q8CCS6 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
22 G3V7Z8 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA)
(12 more)
Nuclear inclusion body GO:0042405
An intranuclear focus at which aggregated proteins have been sequestered.
19 G3V7Z8 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA)
(9 more)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
19 Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA) Q86U42 (/IDA)
(9 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
18 Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS) Q86U42 (/TAS)
(8 more)
Nuclear inclusion body GO:0042405
An intranuclear focus at which aggregated proteins have been sequestered.
6 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q8CCS6 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
6 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q8CCS6 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q28165 (/ISS) Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q8CCS6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q6NVP7 (/ISS) Q7ZXB8 (/ISS) Q9DDY9 (/ISS) Q9DDY9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q6TY21 (/IDA) Q804A5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8CCS6 (/ISO)
Nuclear inclusion body GO:0042405
An intranuclear focus at which aggregated proteins have been sequestered.
1 Q8CCS6 (/ISO)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q8CCS6 (/ISO)