The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 210: RNA-binding protein with serine-rich domain 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
68 D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI) D3DU92 (/IPI)
(58 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
34 Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA) Q15287 (/HDA)
(24 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
108 A6QR16 (/ISS) A6QR16 (/ISS) A6QR16 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS)
(98 more)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
108 A6QR16 (/ISS) A6QR16 (/ISS) A6QR16 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS)
(98 more)
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
108 A6QR16 (/ISS) A6QR16 (/ISS) A6QR16 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS)
(98 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
34 Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP)
(24 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
34 Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP) Q15287 (/IMP)
(24 more)
Regulation of alternative mRNA splicing, via spliceosome GO:0000381
Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
RNA export from nucleus GO:0006405
The directed movement of RNA from the nucleus to the cytoplasm.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
Negative regulation of mRNA splicing, via spliceosome GO:0048025
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ASAP complex GO:0061574
A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.
108 A6QR16 (/ISS) A6QR16 (/ISS) A6QR16 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS) Q4R5N1 (/ISS)
(98 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
72 D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA) D3DU92 (/IDA)
(62 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
34 Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS) Q15287 (/TAS)
(24 more)
ASAP complex GO:0061574
A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.
34 Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA) Q15287 (/IDA)
(24 more)
ASAP complex GO:0061574
A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.
34 Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO) Q99M28 (/ISO)
(24 more)