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CATH Superfamily 3.30.70.270

Reverse transcriptase/Diguanylate cyclase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: DNA polymerase V subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
DNA-directed DNA polymerase activity GO:0003887
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 46 P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI) P04152 (/IPI)
(36 more)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
 46 P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP)
(36 more)
SOS response GO:0009432
An error-prone process for repairing damaged microbial DNA.
 46 P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP) P04152 (/IEP)
(36 more)
Translesion synthesis GO:0019985
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
SOS response GO:0009432
An error-prone process for repairing damaged microbial DNA.
 1 Q8E897 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
DNA polymerase V complex GO:0009355
A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 46 P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA) P04152 (/IDA)
(36 more)