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CATH Superfamily 3.30.70.1150

ACT-like. Chain A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ACT-like. Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Nickel-responsive regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 174 P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP)
(164 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
 174 P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI)
(164 more)
Bacterial-type RNA polymerase core promoter sequence-specific DNA binding GO:0000985
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a bacterial gene.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 174 P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP)
(164 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
 174 P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI)
(164 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 174 P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI)
(164 more)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 174 P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP)
(164 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 174 P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI)
(164 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
Negative regulation of DNA-templated transcription, initiation GO:2000143
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.
 174 P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP)
(164 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 174 P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA) P0A6Z6 (/IDA)
(164 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 174 P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP) P0A6Z6 (/IMP)
(164 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 174 P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI) P0A6Z6 (/IPI)
(164 more)