The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"N-acetyl transferase-like
".
FunFam 3: Histone acetyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
4 | M9NEW2 (/IPI) Q7YTZ9 (/IPI) Q9NHW0 (/IPI) Q9VM15 (/IPI) |
|
H3 histone acetyltransferase activity GO:0010484
Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Negative regulation of cell fate specification GO:0009996
Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Sensory organ precursor cell fate determination GO:0016360
The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
4 | M9NEW2 (/IGI) Q7YTZ9 (/IGI) Q9NHW0 (/IGI) Q9VM15 (/IGI) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | M9NEW2 (/TAS) Q7YTZ9 (/TAS) Q9NHW0 (/TAS) Q9VM15 (/TAS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |
|
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
|
4 | M9NEW2 (/IMP) Q7YTZ9 (/IMP) Q9NHW0 (/IMP) Q9VM15 (/IMP) |
|
Wing disc dorsal/ventral pattern formation GO:0048190
The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
|
4 | M9NEW2 (/IGI) Q7YTZ9 (/IGI) Q9NHW0 (/IGI) Q9VM15 (/IGI) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | M9NEW2 (/IDA) Q7YTZ9 (/IDA) Q9NHW0 (/IDA) Q9VM15 (/IDA) |