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CATH Superfamily 3.30.590.10

Glutamine synthetase/guanido kinase, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutamine synthetase/guanido kinase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Glutamine synthetase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamine synthetase. [EC: 6.3.1.2]
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
  • Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.
  • Several types have been described, differing in their oligomeric structures and cofactor requirements.
 168 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85
(158 more...)
Protein S-acyltransferase. [EC: 2.3.1.225]
Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
  • The enzyme catalyzes the posttranslational protein palmitoylation that plays a role in protein-membrane interactions, protein trafficking, and enzyme activity.
  • Palmitoylation increases the hydrophobicity of proteins or protein domains and contributes to their membrane association.
 150 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85 A0A0D9RJ85
(140 more...)