The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aconitase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: 3-isopropylmalate dehydratase large subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
115 P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI) P0A6A6 (/IPI)
(105 more)
Intramolecular transferase activity GO:0016866
Catalysis of the transfer of a functional group from one position to another within a single molecule.
115 P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA)
(105 more)
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
7 Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS)
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
2 P07264 (/IMP) P07264 (/IMP)
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
2 Q5B0P4 (/RCA) Q5B0P4 (/RCA)
3-isopropylmalate dehydratase activity GO:0003861
Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.
1 O14289 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
115 P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA)
(105 more)
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
7 Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS)
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
4 P07264 (/IMP) P07264 (/IMP) Q5B0P4 (/IMP) Q5B0P4 (/IMP)
Branched-chain amino acid metabolic process GO:0009081
The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
2 Q5B0P4 (/RCA) Q5B0P4 (/RCA)
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
2 Q5B0P4 (/IEP) Q5B0P4 (/IEP)
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
1 O14289 (/EXP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
117 P07264 (/IDA) P07264 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA) P0A6A6 (/IDA)
(107 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
7 P9WQF5 (/HDA) P9WQF5 (/HDA) P9WQF5 (/HDA) P9WQF5 (/HDA) P9WQF5 (/HDA) P9WQF5 (/HDA) P9WQF5 (/HDA)
3-isopropylmalate dehydratase complex GO:0009316
A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
7 Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS) Q9KP81 (/ISS)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2 P07264 (/IDA) P07264 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O14289 (/ISO)