The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA ligase/mRNA capping enzyme
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: mRNA-capping enzyme

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O55236 (/IPI) O55236 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI) O60942 (/IPI)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
Polynucleotide 5'-phosphatase activity GO:0004651
Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
RNA guanylyltransferase activity GO:0008192
Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
3 O55236 (/ISS) O55236 (/ISS) Q6NY98 (/ISS)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
3 O55236 (/ISS) O55236 (/ISS) Q6NY98 (/ISS)
MRNA guanylyltransferase activity GO:0004484
Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
2 O55236 (/ISO) O55236 (/ISO)
RNA guanylyltransferase activity GO:0008192
Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
2 O55236 (/ISO) O55236 (/ISO)
Triphosphatase activity GO:0050355
Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
2 O55236 (/ISO) O55236 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
6 O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA) O60942 (/IDA)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
3 O55236 (/ISS) O55236 (/ISS) Q6NY98 (/ISS)
7-methylguanosine mRNA capping GO:0006370
Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
2 O55236 (/ISO) O55236 (/ISO)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
2 O55236 (/ISO) O55236 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS) O60942 (/TAS)