The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutamyl-tRNA reductase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Glutamyl-tRNA reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
36 P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI) P0A6X1 (/IPI)
(26 more)
Glutamyl-tRNA reductase activity GO:0008883
Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
35 P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA)
(25 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
35 P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA)
(25 more)
Glutamyl-tRNA reductase activity GO:0008883
Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
10 Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS)
Glutamyl-tRNA reductase activity GO:0008883
Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
1 P42804 (/TAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protoporphyrinogen IX biosynthetic process from glutamate GO:0019353
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.
35 P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA) P0A6X1 (/IDA)
(25 more)
Porphyrin-containing compound biosynthetic process GO:0006779
The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
10 Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS) Q9KQ24 (/ISS)
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
2 P42804 (/IMP) P49294 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P49294 (/IEP)
Chlorophyll biosynthetic process GO:0015995
The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
1 P42804 (/IMP)
Tetrapyrrole biosynthetic process GO:0033014
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
1 P49294 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 P42804 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 P42804 (/TAS)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
1 P49294 (/IDA)