The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dynein light chain 2a, cytoplasmic
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Ragulator complex protein LAMTOR5 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
27 A0A0C4DGV4 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI) O43504 (/IPI)
(17 more)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Positive regulation of TOR signaling GO:0032008
Any process that activates or increases the frequency, rate or extent of TOR signaling.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Positive regulation of TOR signaling GO:0032008
Any process that activates or increases the frequency, rate or extent of TOR signaling.
27 O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP)
(17 more)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
27 O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP)
(17 more)
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
26 O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS)
(16 more)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
26 O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP)
(16 more)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
26 O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS)
(16 more)
Regulation of macroautophagy GO:0016241
Any process that modulates the frequency, rate or extent of macroautophagy.
26 O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS)
(16 more)
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
26 O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS)
(16 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
26 O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA)
(16 more)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
26 O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA)
(16 more)
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
26 O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP) O43504 (/IMP)
(16 more)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 Q9D1L9 (/ISO)
Positive regulation of TOR signaling GO:0032008
Any process that activates or increases the frequency, rate or extent of TOR signaling.
1 Q9D1L9 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q9D1L9 (/ISO)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
1 Q9D1L9 (/ISO)
Protein localization to lysosome GO:0061462
A process in which a protein is transported to, or maintained in, a location within a lysosome.
1 Q9D1L9 (/ISO)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 Q9D1L9 (/ISO)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
1 O96824 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Ragulator complex GO:0071986
A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases.
61 A7RT29 (/ISS) A9UL91 (/ISS) A9UL91 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS) Q3SZ68 (/ISS)
(51 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
27 A0A0C4DGV4 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA)
(17 more)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
26 O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA)
(16 more)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
26 O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS) O43504 (/TAS)
(16 more)
Ragulator complex GO:0071986
A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases.
26 O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA) O43504 (/IDA)
(16 more)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 Q9D1L9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9D1L9 (/ISO)
Ragulator complex GO:0071986
A eukaryotically conserved protein complex; in humans, it is comprised of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4, and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via LAMTOR1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases.
1 Q9D1L9 (/ISO)