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CATH Superfamily 3.30.450.30

Dynein light chain 2a, cytoplasmic

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Dynein light chain 2a, cytoplasmic
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32: Dynein light chain 2B, cytoplasmic, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
 3 Q57YQ2 (/ISA) Q57YQ2 (/ISA) Q57YQ2 (/ISA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cilium movement involved in cell motility GO:0060294
Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
 4 Q580Q0 (/IMP) Q580Q0 (/IMP) Q580Q0 (/IMP) Q580Q0 (/IMP)
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
 3 Q57YQ2 (/ISA) Q57YQ2 (/ISA) Q57YQ2 (/ISA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 3 Q57YQ2 (/IDA) Q57YQ2 (/IDA) Q57YQ2 (/IDA)
Cytoplasmic dynein complex GO:0005868
Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
 3 Q57YQ2 (/ISA) Q57YQ2 (/ISA) Q57YQ2 (/ISA)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
 3 Q57YQ2 (/IDA) Q57YQ2 (/IDA) Q57YQ2 (/IDA)