The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PAS domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
748
3D
4hqaA00 - 97.9
2
639
3D
5hziB02 - 74.0
4
549
3D
3gdiB02 - 85.3
3
541 - - 69.6
5
523 - - 91.6
6
502
3D
4f3lB02 - 75.2
7
487 - - 91.4
9
475
3D
4lloH00 - 93.5
8
473 - - 90.0
10
433
3D
4f3lB03 - 72.3
11
415 - - 70.3
15
413
3D
4h6jA00 - 92.6
12
408 - - 92.5
13
407
3D
3gdiB01 - 92.5
14
392 - - 76.7
16
334
3D
4f3lA03 - 65.1
17
328 - - 72.2
18
323
3D
2w0nA00 - 96.5
19
304 - - 82.4
20
301 - - 62.5
21
284 - - 95.6
22
278
3D
4f3lA02 - 79.1
23
261 - - 72.1
28
230
3D
5ufpB01 - 63.3
24
223 - - 96.4
25
220 - - 76.6
26
212 - - 57.7
27
206 - - 78.1
29
201 - - 89.4
31
181
3D
5y7wB00 - 54.3
30
180 - - 93.6
32
169 - - 43.0
33
II
168 - - 14.7
35
159
3D
4m4xB00 - 92.1
36
159
3D
2z6cB00 - 79.4
34
158 - - 95.4
37
148
3D
4mn6B00 - 84.7
38
143 - - 57.1
39
142 - - 92.3
41
142
3D
5svwD00 - 83.8
40
139 - - 77.1
42
127
3D
4wn5B00 - 80.6
43
122
3D
2jheD02 - 0.0
48
119
3D
6iouB02 - 98.4
45
116
3D
3by8A00 - 92.6
44
115 - - 68.9
46
108 - - 89.4
47
104 - - 78.3
60
100
3D
2vv8D00 - 98.3
49
93 - - 19.0
50
85 - - 25.0
64
84
3D
3d72B00 - 88.0
51
83 - - 7.2
52
82 - - 46.9
53
75 - - 84.4
54
74 - - 79.8
55
73 - - 74.5
56
71 - - 68.6
57
69 - - 87.2
58
68 - - 25.5
59
66
3D
1ll8A00 - 98.2
61
62 - - 75.4
66
62
3D
3rtyH02 - 81.4
72
57
3D
3rtyH01 - 84.1
62
GGDEF
56 - - 80.2
63
54 - - 74.6
65
53 - - 35.0
68
49 - - 82.6
69
49 - - 80.8
67
49 - - 44.3
71
48 - - 44.6
75
48
3D
4hi4G00 - 89.7
70
48 - - 26.1
74
44 - - 81.7
73
44 - - 77.2
76
42 - - 40.1
77
41 - - 67.2
78
40 - - 49.8
437
40
3D
6mhnA00 - 9.9
79
40 - - 28.7
80
39 - - 75.9
81
39 - - 93.4
82
38 - - 70.3
83
38 - - 3.1
84
37
3D
2v9aB00 - 14.4
85
35 - - 70.7
135
33
3D
5dklB00 - 77.9
86
33 - - 22.2
87
33 - - 76.5
88
31 - - 100.0
89
30 - - 63.6
90
30 - - 77.4
91
29 - - 33.1
92
28 - - 73.6
93
28 - - 20.7
96
27 - - 67.9
94
27 - - 46.3
95
27 - - 6.5
97
27 - - 65.6
98
26 - - 76.0
169
26
3D
5c5kD02 - 92.2
99
25 - - 98.2
101
23 - - 90.6
100
23 - - 67.0
102
22 - - 0.0
104
22 - - 28.9
103
22 - - 76.6
105
21 - - 58.9
106
21 - - 11.9
107
21 - - 14.0
108
20 - - 75.6
109
20 - - 2.1
170
19
3D
1vb6B00 - 19.2
111
19 - - 15.3
148
19
3D
4lrzH02 - 3.4
110
19 - - 0.0
116
17 - - 45.8
112
17 - - 51.3
155
17
3D
5hwwB00 - 96.7
113
17 - - 3.7
115
17 - - 68.2
114
17 - - 76.6
127
16
3D
3by9B02 - 68.4
117
16 - - 52.1
120
16 - - 97.3
119
16 - - 61.0
118
16 - - 70.5
121
15 - - 25.2
122
15 - - 32.0
123
15 - - 38.6
124
14 - - 17.6
125
14 - - 0.7
126
14 - - 11.1
136
13 - - 63.8
128
13 - - 18.0
132
13 - - 94.2
129
13 - - 90.8
131
13 - - 10.1
130
13 - - 13.5
133
13 - - 0.0
134
13 - - 0.0
137
12 - - 0.0
142
12 - - 16.6
139
12 - - 3.2
141
12 - - 43.4
144
12 - - 81.6
138
12 - - 51.7
140
12 - - 3.5
143
12 - - 9.4
153
11 - - 67.8
154
11 - - 77.2
147
11 - - 2.5
149
11 - - 72.5
145
11 - - 20.0
152
11 - - 10.4
157
11 - - 43.2
146
11 - - 23.7
151
11 - - 44.6
156
11 - - 92.6
197
11
3D
2ykhB02 - 0.0
150
11 - - 36.2
158
10 - - 13.1
165
10 - - 18.4
168
10 - - 87.5
161
10 - - 0.0
164
10 - - 7.8
160
10 - - 19.8
167
10 - - 14.3
163
10 - - 11.0
159
10 - - 5.8
162
10 - - 9.1
166
10 - - 9.5
180
9 - - 13.1
187
9 - - 79.7
175
9 - - 13.6
184
9 - - 37.9
181
9 - - 5.6
178
9 - - 0.0
174
9 - - 10.1
183
9 - - 0.8
179
9 - - 37.5
177
9 - - 0.0
182
9 - - 23.6
186
9 - - 82.8
173
9 - - 29.0
171
9 - - 26.6
176
9 - - 8.8
172
9 - - 15.2
185
9 - - 96.5
191
8 - - 0.0
212
8 - - 47.2
207
8 - - 10.5
198
8 - - 15.2
202
8 - - 7.7
209
8 - - 58.3
210
8 - - 7.7
213
8 - - 71.1
200
8 - - 12.2
192
8 - - 5.5
199
8 - - 0.0
195
8 - - 0.0
188
Direct oxygen sensor protein
8 - - 1.0
203
8 - - 0.0
204
8 - - 0.0
211
8 - - 47.7
193
8 - - 9.8
189
8 - - 36.9
205
8 - - 17.5
214
8 - - 30.0
196
8 - - 84.1
206
8 - - 3.3
194
8 - - 2.9
208
8 - - 48.3
201
8 - - 0.0
190
8 - - 4.1
225
7 - - 0.0
229
7 - - 36.5
222
7 - - 15.0
217
7 - - 3.3
224
7 - - 0.0
228
7 - - 13.4
218
7 - - 7.4
221
7 - - 0.0
227
7 - - 7.1
230
7 - - 0.0
219
7 - - 0.0
220
7 - - 8.3
226
7 - - 51.6
215
7 - - 7.9
231
7 - - 83.3
223
7 - - 13.0
216
7 - - 10.7
246
6 - - 15.2
262
6 - - 40.7
232
6 - - 17.9
257
6 - - 9.1
247
6 - - 14.5
252
6 - - 11.9
242
6 - - 1.5
254
6 - - 1.0
263
6 - - 1.5
267
6 - - 79.6
233
6 - - 0.0
243
6 - - 0.0
268
6 - - 88.4
238
6 - - 14.4
253
6 - - 10.6
258
6 - - 8.6
248
6 - - 0.0
325
6
3D
4dj2D01 - 19.6
236
6 - - 0.0
234
6 - - 0.0
260
6 - - 0.0
264
6 - - 7.1
255
6 - - 15.2
250
6 - - 0.0
259
6 - - 4.2
249
Regulator of sigma subunit
6 - - 4.1
240
6 - - 0.0
239
6 - - 0.0
244
6 - - 0.0
237
6 - - 4.3
235
6 - - 0.0
265
6 - - 0.7
251
6 - - 14.0
256
6 - - 13.5
245
6 - - 8.9
241
6 - - 75.6
266
6 - - 79.7
261
6 - - 15.9
285
5 - - 0.0
301
5 - - 38.6
272
5 - - 1.0
294
5 - - 6.0
278
5 - - 0.0
335
5
3D
4l9eA00 - 7.4
299
5 - - 0.0
281
5 - - 2.8
284
5 - - 14.1
289
5 - - 11.2
290
5 - - 7.3
271
5 - - 1.0
279
5 - - 0.0
293
5 - - 0.0
280
5 - - 5.5
273
5 - - 30.7
302
5 - - 51.6
298
5 - - 0.0
288
5 - - 4.5
287
5 - - 0.0
274
5 - - 0.0
303
5 - - 86.9
276
5 - - 21.1
269
5 - - 10.2
297
GGDEF
5 - - 7.5
283
5 - - 18.0
295
5 - - 40.9
300
5 - - 6.2
286
5 - - 0.0
296
GGDEF
5 - - 8.3
275
5 - - 0.0
292
5 - - 8.0
291
5 - - 77.6
270
5 - - 0.0
282
5 - - 25.9
277
5 - - 0.0
304
5 - - 82.2
340
eag-related
4 - - 70.8
311
4 - - 6.2
308
4 - - 0.0
323
4 - - 1.0
330
4 - - 23.4
307
4 - - 0.0
326
4 - - 5.5
315
4 - - 1.0
305
4 - - 0.0
317
4 - - 8.3
319
4 - - 3.2
344
4 - - 74.1
336
4 - - 11.5
342
4 - - 73.6
341
4 - - 71.3
309
4 - - 17.8
329
4 - - 0.0
346
4 - - 76.6
322
4 - - 1.6
310
4 - - 9.4
316
4 - - 6.9
314
4 - - 2.8
334
4 - - 0.0
339
4 - - 1.1
345
4 - - 64.0
318
4 - - 3.1
337
4 - - 0.0
333
4 - - 0.0
347
4 - - 79.8
320
4 - - 0.0
338
4 - - 7.2
328
4 - - 0.0
313
4 - - 0.0
331
4 - - 21.6
348
4 - - 82.6
324
4 - - 0.0
312
4 - - 5.5
332
4 - - 68.1
327
4 - - 0.0
343
4 - - 77.1
321
4 - - 0.0
306
4 - - 0.0
350
3 - - 0.0
391
3 - - 4.4
366
3 - - 4.4
349
3 - - 0.0
359
3 - - 0.0
360
3 - - 8.4
353
3 - - 73.6
375
3 - - 0.0
387
3 - - 0.0
395
3 - - 0.0
361
3 - - 0.0
383
3 - - 0.0
365
3 - - 0.0
382
3 - - 16.5
367
3 - - 5.9
351
3 - - 10.6
392
3 - - 0.0
386
3 - - 0.0
372
3 - - 24.7
354
3 - - 1.8
355
3 - - 3.4
362
3 - - 0.0
376
3 - - 6.8
371
3 - - 0.0
396
3 - - 78.3
356
3 - - 9.6
378
3 - - 0.0
389
3 - - 7.9
381
3 - - 9.1
373
3 - - 41.3
393
3 - - 7.6
385
3 - - 0.0
377
3 - - 5.7
363
3 - - 10.4
397
3 - - 82.1
357
3 - - 5.4
390
3 - - 0.0
358
3 - - 5.8
388
3 - - 5.9
364
3 - - 42.3
379
3 - - 10.3
370
3 - - 6.9
380
3 - - 0.0
352
3 - - 66.3
369
3 - - 0.0
394
3 - - 0.0
368
3 - - 7.1
374
3 - - 0.0
384
3 - - 10.4
512
2 - - 10.4
463
2 - - 11.1
458
2 - - 0.0
517
2 - - 9.5
495
2 - - 0.0
486
2 - - 0.0
444
2 - - 3.7
508
2 - - 0.0
506
2 - - 0.0
456
2 - - 0.0
468
2 - - 1.5
413
2 - - 0.0
432
2 - - 38.1
526
2 - - 0.0
477
2 - - 29.3
449
2 - - 32.8
501
2 - - 7.7
490
2 - - 10.9
461
2 - - 0.0
425
2 - - 0.0
520
2 - - 10.8
532
2 - - 41.8
412
2 - - 7.2
440
2 - - 4.1
467
2 - - 0.0
481
2 - - 0.0
474
2 - - 0.0
472
2 - - 0.0
529
2 - - 0.0
457
2 - - 7.0
505
2 - - 0.0
419
2 - - 0.0
406
2 - - 11.1
421
2 - - 0.0
491
2 - - 0.0
408
2 - - 9.2
443
2 - - 0.0
431
2 - - 0.0
509
2 - - 0.0
523
2 - - 9.2
453
2 - - 13.1
488
2 - - 0.0
405
2 - - 3.9
507
2 - - 0.0
399
2 - - 1.0
436
2 - - 7.6
525
2 - - 0.0
427
2 - - 0.0
426
2 - - 0.0
498
2 - - 0.0
483
2 - - 0.0
533
2 - - 46.5
462
2 - - 0.0
414
2 - - 6.5
476
2 - - 0.0
469
2 - - 0.0
511
2 - - 3.0
471
2 - - 0.0
502
2 - - 0.0
423
2 - - 0.0
422
2 - - 0.0
402
2 - - 0.0
464
2 - - 1.1
439
2 - - 3.2
407
2 - - 0.0
435
2 - - 0.0
494
2 - - 10.0
487
2 - - 0.0
448
2 - - 3.6
482
2 - - 4.7
499
2 - - 1.0
450
2 - - 40.9
473
2 - - 8.3
528
2 - - 5.5
451
2 - - 3.5
454
2 - - 0.0
410
2 - - 0.0
430
2 - - 0.0
447
2 - - 2.0
415
2 - - 0.0
480
2 - - 45.3
438
2 - - 10.3
417
2 - - 0.0
493
2 - - 1.7
400
2 - - 2.9
534
2 - - 43.5
475
2 - - 0.0
515
2 - - 0.0
519
2 - - 0.0
446
2 - - 0.0
510
2 - - 9.2
424
2 - - 0.0
434
2 - - 3.7
442
2 - - 0.0
465
2 - - 0.0
479
2 - - 39.4
524
2 - - 0.0
503
2 - - 9.5
484
2 - - 0.0
522
2 - - 0.0
459
2 - - 3.6
401
2 - - 1.7
404
2 - - 0.0
516
2 - - 10.5
455
2 - - 0.0
530
2 - - 0.0
470
2 - - 4.9
527
2 - - 0.0
418
2 - - 5.1
485
2 - - 0.0
460
2 - - 0.8
452
2 - - 0.0
416
2 - - 0.0
496
2 - - 0.0
445
2 - - 0.0
441
2 - - 1.1
428
2 - - 0.0
500
2 - - 0.0
514
2 - - 0.0
513
2 - - 2.2
492
2 - - 0.0
429
2 - - 0.0
409
2 - - 0.0
489
2 - - 0.0
521
2 - - 0.0
433
2 - - 44.4
518
2 - - 7.9
497
2 - - 7.4
411
2 - - 0.0
478
2 - - 13.9
398
2 - - 10.3
504
2 - - 0.0
531
2 - - 30.8
420
2 - - 0.0
403
2 - - 0.0
466
2 - - 2.3
569
1 - - 0.0
686
1 - - 0.0
690
1 - - 0.0
536
1 - - 0.0
558
1 - - 0.0
573
1 - - 0.0
638
1 - - 0.0
661
1 - - 0.0
581
1 - - 0.0
678
1 - - 0.0
652
1 - - 0.0
606
1 - - 0.0
666
1 - - 0.0
545
1 - - 0.0
588
1 - - 0.0
542
1 - - 0.0
574
1 - - 0.0
660
1 - - 0.0
566
1 - - 0.0
604
1 - - 0.0
659
1 - - 0.0
682
1 - - 0.0
626
1 - - 0.0
539
1 - - 0.0
584
1 - - 0.0
665
1 - - 0.0
649
1 - - 0.0
648
1 - - 0.0
642
1 - - 0.0
681
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
563
1 - - 0.0
673
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
636
1 - - 0.0
600
1 - - 0.0
696
1 - - 0.0
670
1 - - 0.0
625
1 - - 0.0
570
1 - - 0.0
655
1 - - 0.0
597
1 - - 0.0
559
1 - - 0.0
580
1 - - 0.0
675
1 - - 0.0
662
1 - - 0.0
653
1 - - 0.0
685
1 - - 0.0
595
1 - - 0.0
644
1 - - 0.0
568
1 - - 0.0
691
1 - - 0.0
650
1 - - 0.0
629
1 - - 0.0
615
1 - - 0.0
635
1 - - 0.0
575
1 - - 0.0
699
1 - - 0.0
543
1 - - 0.0
603
1 - - 0.0
565
1 - - 0.0
674
1 - - 0.0
553
1 - - 0.0
555
1 - - 0.0
680
1 - - 0.0
679
1 - - 0.0
647
1 - - 0.0
593
1 - - 0.0
641
1 - - 0.0
616
1 - - 0.0
640
1 - - 0.0
562
1 - - 0.0
599
1 - - 0.0
587
1 - - 0.0
609
1 - - 0.0
624
1 - - 0.0
656
1 - - 0.0
596
1 - - 0.0
613
1 - - 0.0
547
1 - - 0.0
631
1 - - 0.0
560
1 - - 0.0
634
1 - - 0.0
578
1 - - 0.0
695
1 - - 0.0
540
1 - - 0.0
684
1 - - 0.0
571
1 - - 0.0
594
1 - - 0.0
586
1 - - 0.0
633
1 - - 0.0
646
1 - - 0.0
556
PhoR1
1 - - 0.0
671
1 - - 0.0
692
1 - - 0.0
663
1 - - 0.0
658
1 - - 0.0
549
1 - - 0.0
614
1 - - 0.0
583
1 - - 0.0
591
1 - - 0.0
689
1 - - 0.0
619
1 - - 0.0
698
1 - - 0.0
621
1 - - 0.0
598
1 - - 0.0
602
1 - - 0.0
612
1 - - 0.0
564
1 - - 0.0
657
1 - - 0.0
576
1 - - 0.0
544
1 - - 0.0
623
1 - - 0.0
628
1 - - 0.0
630
1 - - 0.0
608
1 - - 0.0
667
1 - - 0.0
561
1 - - 0.0
550
1 - - 0.0
592
1 - - 0.0
654
1 - - 0.0
572
1 - - 0.0
548
1 - - 0.0
627
1 - - 0.0
637
1 - - 0.0
579
1 - - 0.0
535
1 - - 0.0
683
1 - - 0.0
541
1 - - 0.0
567
1 - - 0.0
605
1 - - 0.0
607
1 - - 0.0
694
1 - - 0.0
582
1 - - 0.0
557
1 - - 0.0
672
1 - - 0.0
677
1 - - 0.0
590
1 - - 0.0
664
1 - - 0.0
617
1 - - 0.0
651
1 - - 0.0
632
1 - - 0.0
610
1 - - 0.0
645
1 - - 0.0
589
1 - - 0.0
687
1 - - 0.0
620
1 - - 0.0
611
1 - - 0.0
585
1 - - 0.0
622
1 - - 0.0
538
1 - - 0.0
668
1 - - 0.0
688
1 - - 0.0
693
1 - - 0.0
601
1 - - 0.0
551
1 - - 0.0
697
1 - - 0.0
669
1 - - 0.0
639
1 - - 0.0
577
1 - - 0.0
643
1 - - 0.0
676
1 - - 0.0
618
1 - - 0.0