The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Influenza virus non-structural protein, effector domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Influenza virus non-structural protein, effector domain

NS1 (non-structural protein) is a virulence factor, a homodimeric RNA-binding protein that is required for viral replication. The effector domain (ED) is able to interact with a variety of cellular and viral targets. PFAM:PF00600,DOI:10.1107/S1744309111019312

GO Diversity

Unique GO annotations
17 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
6376 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 69
Domain clusters (>95% seq id): 12
Domain clusters (>35% seq id): 2
Unique PDBs: 27
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 17
Unique Species: 6376