The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 567:

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 A0A2R8Q0R2 (/IDA)
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
1 A0A2R8Q0R2 (/IGI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 A0A2R8Q0R2 (/IGI)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 A0A2R8Q0R2 (/IMP)
Somite specification GO:0001757
The process in which individual somites establish identity during embryogenesis.
1 A0A2R8Q0R2 (/IGI)
Cell migration involved in sprouting angiogenesis GO:0002042
The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
1 A0A2R8Q0R2 (/IMP)
Lens morphogenesis in camera-type eye GO:0002089
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
1 A0A2R8Q0R2 (/IMP)
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 A0A2R8Q0R2 (/IMP)
Heart field specification GO:0003128
The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.
1 A0A2R8Q0R2 (/IGI)
Heart jogging GO:0003146
The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
1 A0A2R8Q0R2 (/IMP)
Cardioblast migration to the midline involved in heart rudiment formation GO:0003319
The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.
1 A0A2R8Q0R2 (/IGI)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 A0A2R8Q0R2 (/IMP)
Ventricular system development GO:0021591
The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.
1 A0A2R8Q0R2 (/IMP)
Adrenal gland development GO:0030325
The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
1 A0A2R8Q0R2 (/IMP)
Embryonic heart tube development GO:0035050
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
1 A0A2R8Q0R2 (/IGI)
Embryonic heart tube development GO:0035050
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
1 A0A2R8Q0R2 (/IMP)
Establishment of epithelial cell apical/basal polarity GO:0045198
The specification and formation of the apicobasal polarity of an epithelial cell.
1 A0A2R8Q0R2 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
1 A0A2R8Q0R2 (/IGI)
Endocardial cell differentiation GO:0060956
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.
1 A0A2R8Q0R2 (/IMP)
Lens fiber cell morphogenesis GO:0070309
The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
1 A0A2R8Q0R2 (/IMP)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
1 A0A2R8Q0R2 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Interstitial matrix GO:0005614
A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
1 A0A2R8Q0R2 (/IMP)