The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ribonuclease H-like superfamily/Ribonuclease H
".
FunFam 41: Exonuclease 3'-5' domain containing 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
1 | Q9VGN7 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9NVH0 (/IPI) |
|
Single-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008310
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
|
1 | Q9NVH0 (/IDA) |
|
Single-stranded DNA 3'-5' exodeoxyribonuclease activity GO:0008310
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
|
1 | Q8VEG4 (/ISO) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
1 | Q9NVH0 (/IDA) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
1 | Q8VEG4 (/ISO) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
1 | Q9VGN7 (/ISS) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
|
1 | Q9NVH0 (/IDA) |
|
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
|
1 | Q8VEG4 (/ISO) |
|
DNA double-strand break processing GO:0000729
The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.
|
1 | Q9NVH0 (/IDA) |
|
DNA double-strand break processing GO:0000729
The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.
|
1 | Q8VEG4 (/ISO) |
|
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
|
1 | Q9NVH0 (/IDA) |
|
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
|
1 | Q8VEG4 (/ISO) |
|
Somatic cell DNA recombination GO:0016444
Recombination occurring within or between DNA molecules in somatic cells.
|
1 | Q9VGN7 (/IMP) |
|
Positive regulation of mitochondrial translation GO:0070131
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
|
1 | Q9VGN7 (/IMP) |
|
Nucleic acid phosphodiester bond hydrolysis GO:0090305
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
|
1 | Q9NVH0 (/IDA) |
|
Nucleic acid phosphodiester bond hydrolysis GO:0090305
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
|
1 | Q8VEG4 (/ISO) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9VGN7 (/IDA) |