The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Enolase-like, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Enolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 47 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
303 A0A077XEH2 (/IPI) A0A077XEH2 (/IPI) C1G9X3 (/IPI) C1G9X3 (/IPI) C1G9X3 (/IPI) D5H2W5 (/IPI) D5H2W5 (/IPI) O51312 (/IPI) P00925 (/IPI) P00925 (/IPI)
(293 more)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
233 A4VWH9 (/IDA) B8Q027 (/IDA) E9BC06 (/IDA) E9BC06 (/IDA) E9BC06 (/IDA) O51312 (/IDA) P04764 (/IDA) P04764 (/IDA) P07323 (/IDA) P0A6P9 (/IDA)
(223 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
198 P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA) P0A6P9 (/IDA)
(188 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
188 P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI)
(178 more)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
65 B5LBH7 (/ISS) B5LBH7 (/ISS) B5LBH7 (/ISS) O51312 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P21550 (/ISS)
(55 more)
Laminin binding GO:0043236
Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells.
34 D5H2W5 (/IDA) D5H2W5 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA)
(24 more)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
28 A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI) A0A0L0LUA6 (/IPI)
(18 more)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
24 D5H2W5 (/IDA) D5H2W5 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA) Q2G028 (/IDA)
(14 more)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
19 K1J238 (/IMP) K1J238 (/IMP) K1J238 (/IMP) P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00925 (/IMP) P00925 (/IMP) P00925 (/IMP)
(9 more)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
14 P0CX10 (/ISA) P0CX10 (/ISA) P0CX10 (/ISA) P0CX10 (/ISA) P0CX10 (/ISA) P0CX10 (/ISA) P0CX10 (/ISA) P0CX11 (/ISA) P0CX11 (/ISA) P0CX11 (/ISA)
(4 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
10 P04764 (/IDA) P04764 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P07323 (/IDA) P15429 (/IDA)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
9 P0CX11 (/IGI) P0CX11 (/IGI) P0CX11 (/IGI) P0CX11 (/IGI) P0CX11 (/IGI) P0CX11 (/IGI) P0CX11 (/IGI) P42222 (/IGI) P42222 (/IGI)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
9 P07323 (/TAS) P09104 (/TAS) P09104 (/TAS) P09104 (/TAS) P09104 (/TAS) P09104 (/TAS) P13929 (/TAS) P13929 (/TAS) P13929 (/TAS)
Fibronectin binding GO:0001968
Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
8 Q88VW2 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI) Q88YH3 (/IPI)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
7 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO) Q4QFL8 (/ISO)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
6 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
6 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
6 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
6 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO)
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
6 P06733 (/IPI) P06733 (/IPI) P06733 (/IPI) P06733 (/IPI) P06733 (/IPI) P06733 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
IgE binding GO:0019863
Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype.
4 Q96X30 (/IDA) Q96X30 (/IDA) Q96X30 (/IDA) Q96X30 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
4 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA) P15429 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
3 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 P17182 (/IDA) P17182 (/IDA) P17182 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 P04764 (/IPI) P04764 (/IPI) P07323 (/IPI)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
3 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO)
Zymogen binding GO:0035375
Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
3 Q8DTS9 (/IPI) Q8DTS9 (/IPI) Q8DTS9 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 B5LBH7 (/ISS) B5LBH7 (/ISS) B5LBH7 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 P17182 (/IPI) P17182 (/IPI) P17182 (/IPI)
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
3 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P25696 (/IDA) P25696 (/IDA)
Protein-glutamine gamma-glutamyltransferase activity GO:0003810
Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.
2 P30575 (/IDA) P30575 (/IDA)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
2 P40370 (/ISM) Q8NKC2 (/ISM)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 P25696 (/IDA) P25696 (/IDA)
High molecular weight kininogen binding GO:0030985
Interacting selectively and non-covalently with a kininogen of high molecular mass.
2 P30575 (/IDA) P30575 (/IDA)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
2 P04764 (/IPI) P04764 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q27727 (/IMP)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q4QFL8 (/ISO)
Phosphopyruvate hydratase activity GO:0004634
Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
1 Q5B135 (/RCA)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q3HL75 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 A4VWH9 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q27727 (/IMP)
Fibrinogen binding GO:0070051
Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
1 A4VWH9 (/IPI)

There are 82 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
202 K1J238 (/IMP) K1J238 (/IMP) K1J238 (/IMP) P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00925 (/IMP) P00925 (/IMP) P00925 (/IMP)
(192 more)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
58 B5LBH7 (/ISS) B5LBH7 (/ISS) B5LBH7 (/ISS) O51312 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P09104 (/ISS) P21550 (/ISS)
(48 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
17 O57391 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P07322 (/TAS) P09104 (/TAS) P09104 (/TAS)
(7 more)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
14 Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS)
(4 more)
Activation of immune response GO:0002253
Any process that initiates an immune response.
14 Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA)
(4 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
14 Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS) Q8IJN7 (/TAS)
(4 more)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
14 P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P09104 (/TAS) P09104 (/TAS) P09104 (/TAS) P09104 (/TAS)
(4 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
9 P00924 (/IEP) P00924 (/IEP) P00924 (/IEP) P00924 (/IEP) P00925 (/IEP) P00925 (/IEP) P00925 (/IEP) P00925 (/IEP) P00925 (/IEP)
Regulation of vacuole fusion, non-autophagic GO:0032889
Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
9 P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA)
Regulation of vacuole fusion, non-autophagic GO:0032889
Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
9 P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00924 (/IMP) P00925 (/IMP) P00925 (/IMP) P00925 (/IMP) P00925 (/IMP) P00925 (/IMP)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
8 A4VWH9 (/IDA) O51312 (/IDA) P04764 (/IDA) P04764 (/IDA) P07323 (/IDA) P17182 (/IDA) P17182 (/IDA) P17182 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
6 P06733 (/IEP) P06733 (/IEP) P06733 (/IEP) P06733 (/IEP) P06733 (/IEP) P06733 (/IEP)
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
6 P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
6 P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP)
Positive regulation of muscle contraction GO:0045933
Any process that activates or increases the frequency, rate or extent of muscle contraction.
6 P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
6 P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP) P06733 (/IMP)
Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway GO:1903298
Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway GO:1903298
Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
6 P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI)
Positive regulation of ATP biosynthetic process GO:2001171
Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
6 P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
Positive regulation of ATP biosynthetic process GO:2001171
Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
6 P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI) P06733 (/IGI)
Interaction with host via substance in symbiont cell outer membrane GO:0044045
An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.
5 Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA)
Interaction with host GO:0051701
An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
4 C1G9X3 (/IMP) C1G9X3 (/IMP) C1G9X3 (/IMP) Q7YZX3 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
3 P17182 (/IMP) P17182 (/IMP) P17182 (/IMP)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
3 O57391 (/TAS) P07322 (/TAS) P51913 (/TAS)
Entry into host cell GO:0030260
The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 A0A077XEH2 (/IDA) A0A077XEH2 (/IDA) Q27727 (/IDA)
Entry into host cell GO:0030260
The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 C1G9X3 (/IMP) C1G9X3 (/IMP) C1G9X3 (/IMP)
Interaction with host via substance in symbiont surface GO:0044044
An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 K1J238 (/IMP) K1J238 (/IMP) K1J238 (/IMP)
Symbiont process GO:0044403
A process carried out by symbiont gene products that enables the interaction between two organisms living together in more or less intimate association. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.
3 A0A077XEH2 (/IDA) A0A077XEH2 (/IDA) Q27727 (/IDA)
Adhesion of symbiont to host epithelial cell GO:0044651
The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
3 C1G9X3 (/IMP) C1G9X3 (/IMP) C1G9X3 (/IMP)
Positive regulation of binding GO:0051099
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
3 P17182 (/IMP) P17182 (/IMP) P17182 (/IMP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
3 B5LBH7 (/ISS) B5LBH7 (/ISS) B5LBH7 (/ISS)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Modulation by symbiont of defense-related host nitric oxide production GO:0052163
Any process in which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 E9BC06 (/IDA) E9BC06 (/IDA) E9BC06 (/IDA)
Modulation by symbiont of host immune response GO:0052553
Any process in which an organism modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 E9BC06 (/IDA) E9BC06 (/IDA) E9BC06 (/IDA)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Cellular response to interleukin-7 GO:0098761
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
3 P17182 (/IDA) P17182 (/IDA) P17182 (/IDA)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
2 O51312 (/IDA) P07323 (/IDA)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
2 P30575 (/ISS) P30575 (/ISS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 P25696 (/IMP) P25696 (/IMP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P25696 (/IMP) P25696 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P25696 (/IEP) P25696 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
2 P25696 (/IEP) P25696 (/IEP)
Substantia nigra development GO:0021762
The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).
2 E5RGZ4 (/HEP) E5RGZ4 (/HEP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 P30575 (/IMP) P30575 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
2 P30575 (/IMP) P30575 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 P07323 (/IEP) P15429 (/IEP)
Fibrinolysis GO:0042730
A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
2 P30575 (/IPI) P30575 (/IPI)
Entry into host GO:0044409
Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2 P30575 (/IPI) P30575 (/IPI)
Induction by symbiont of host defense response GO:0044416
The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2 P30575 (/IDA) P30575 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 P25696 (/IEP) P25696 (/IEP)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
2 P40370 (/ISM) Q8NKC2 (/ISM)
ERK1 and ERK2 cascade GO:0070371
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
2 P04764 (/IDA) P04764 (/IDA)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P04764 (/IDA) P04764 (/IDA)
Fungal-type cell wall organization or biogenesis GO:0071852
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.
2 P30575 (/IMP) P30575 (/IMP)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 Q5B135 (/RCA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 Q5B135 (/RCA)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P15429 (/IEP)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
1 Q9C9C4 (/IDA)
Trichome morphogenesis GO:0010090
The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
1 Q9C9C4 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P07323 (/IEP)
Carbon utilization GO:0015976
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
1 Q5B135 (/IMP)
Antibacterial humoral response GO:0019731
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
1 A4VWH9 (/IDA)
Sexual reproduction GO:0019953
A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
1 Q54RK5 (/IEP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 P07323 (/IEP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 P15007 (/IMP)
Skeletal muscle tissue regeneration GO:0043403
The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
1 P15429 (/IEP)
Modification by symbiont of host morphology or physiology GO:0044003
The process in which a symbiont organism effects a change in the structure or processes of its host organism.
1 O51312 (/IDA)
Interaction with host via substance in symbiont surface GO:0044044
An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q3HL75 (/IDA)
Interaction with host via substance in symbiont cell outer membrane GO:0044045
An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 A4VWH9 (/IMP)
Multicellular organismal reproductive process GO:0048609
The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
1 P07323 (/IEP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 A4VWH9 (/IDA)
Positive regulation of fibrinolysis GO:0051919
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
1 O51312 (/IDA)
Negative regulation by symbiont of entry into host cell via phagocytosis GO:0052067
Any process in which an organism stops or prevents itself undergoing phagocytosis into a cell in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 A4VWH9 (/IMP)
Positive regulation by symbiont of host defense response GO:0052509
Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 A4VWH9 (/IDA)
Negative regulation of phagocytosis, engulfment GO:0060101
Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
1 A4VWH9 (/IMP)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q5B135 (/IEP)
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
1 Q5B135 (/IEP)
Regulation of neuron death GO:1901214
Any process that modulates the frequency, rate or extent of neuron death.
1 P07323 (/IGI)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1 P07323 (/IMP)

There are 67 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
245 A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A077XEH2 (/IDA) A0A077XEH2 (/IDA) E5RGZ4 (/IDA) E5RGZ4 (/IDA)
(235 more)
Phosphopyruvate hydratase complex GO:0000015
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
207 P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P04764 (/IDA)
(197 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
198 P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P0A6P9 (/HDA)
(188 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
194 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P0A6P9 (/HDA) P0A6P9 (/HDA) P0A6P9 (/HDA) P0A6P9 (/HDA)
(184 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
188 P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI) P0A6P9 (/IPI)
(178 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
67 A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA) A0A0L0LUA6 (/IDA)
(57 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
48 A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) A0A024R4F1 (/IDA) E5RGZ4 (/IDA) E5RGZ4 (/IDA) P04764 (/IDA) P04764 (/IDA)
(38 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
44 A4VWH9 (/IDA) P04764 (/IDA) P04764 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P07323 (/IDA)
(34 more)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
35 A4VWH9 (/IDA) G8BCT3 (/IDA) P04764 (/IDA) P04764 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA)
(25 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
20 P25696 (/IDA) P25696 (/IDA) P30575 (/IDA) P30575 (/IDA) Q7YZX3 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA)
(10 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
20 O51312 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P09104 (/IDA) P09104 (/IDA) P09104 (/IDA)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
17 O57391 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P06733 (/TAS) P07322 (/TAS) P09104 (/TAS) P09104 (/TAS)
(7 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
16 P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P15007 (/HDA)
(6 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
14 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P09104 (/HDA) P09104 (/HDA) P09104 (/HDA) P09104 (/HDA)
(4 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
14 Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA)
(4 more)
Food vacuole GO:0020020
Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.
14 Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA) Q8IJN7 (/IDA)
(4 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
14 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P09104 (/HDA) P09104 (/HDA) P09104 (/HDA) P09104 (/HDA)
(4 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P25696 (/IDA)
(1 more)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
10 Q38BV6 (/IDA) Q38BV6 (/IDA) Q38BV6 (/IDA) Q38BV6 (/IDA) Q38BV6 (/IDA) Q9NDH8 (/IDA) Q9NDH8 (/IDA) Q9NDH8 (/IDA) Q9NDH8 (/IDA) Q9NDH8 (/IDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
9 P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00924 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA) P00925 (/HDA)
Cell cortex region GO:0099738
The complete extent of cell cortex that underlies some some region of the plasma membrane
9 P04764 (/IDA) P04764 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P06733 (/IDA) P07323 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P06733 (/HDA) P40370 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P00924 (/HDA) P15007 (/HDA) P42222 (/HDA) P42222 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO) Q4QFL8 (/ISO)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
6 P9WNL1 (/HDA) P9WNL1 (/HDA) P9WNL1 (/HDA) P9WNL1 (/HDA) P9WNL1 (/HDA) P9WNL1 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P06733 (/IC) P06733 (/IC) P06733 (/IC) P06733 (/IC) P06733 (/IC) P06733 (/IC)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
6 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO) P21550 (/ISO)
External side of cell outer membrane GO:0031240
The side of the outer membrane that is opposite to the side that faces the periplasm of the cell.
6 O51312 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA) Q9JZ53 (/IDA)
Phosphopyruvate hydratase complex GO:0000015
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 P30575 (/IDA) P30575 (/IDA) Q8DTS9 (/IDA) Q8DTS9 (/IDA) Q8DTS9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 B5LBH7 (/ISS) B5LBH7 (/ISS) B5LBH7 (/ISS) Q27527 (/ISS) Q9XSJ4 (/ISS)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
5 P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA) P00925 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
5 P17182 (/HDA) P17182 (/HDA) P17182 (/HDA) P17183 (/HDA) P17183 (/HDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Cell cortex region GO:0099738
The complete extent of cell cortex that underlies some some region of the plasma membrane
5 P17182 (/ISO) P17182 (/ISO) P17182 (/ISO) P17183 (/ISO) P17183 (/ISO)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 P25696 (/IDA) P25696 (/IDA) Q9C9C4 (/IDA)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
3 P30575 (/IDA) P30575 (/IDA) Q3HL75 (/IDA)
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
3 P17182 (/IDA) P17182 (/IDA) P17182 (/IDA)
Pellicle GO:0020039
The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.
3 A0A077XEH2 (/IDA) A0A077XEH2 (/IDA) Q27727 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
3 P04764 (/IDA) P04764 (/IDA) P07323 (/IDA)
Phosphopyruvate hydratase complex GO:0000015
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
2 P04764 (/IC) P04764 (/IC)
Phosphopyruvate hydratase complex GO:0000015
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
2 P30575 (/ISS) P30575 (/ISS)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
2 P17183 (/IDA) P17183 (/IDA)
Mitochondrial envelope GO:0005740
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
2 P25696 (/IDA) P25696 (/IDA)
Fungal-type cell wall GO:0009277
A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
2 P30575 (/IDA) P30575 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 P25696 (/IDA) P25696 (/IDA)
Yeast-form cell wall GO:0030445
The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
2 P30575 (/IDA) P30575 (/IDA)
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
2 P30575 (/IDA) P30575 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P17183 (/IDA) P17183 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
2 P17183 (/IDA) P17183 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 P25696 (/IDA) P25696 (/IDA)
Fungal biofilm matrix GO:0062040
An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
2 P30575 (/IDA) P30575 (/IDA)
Phosphopyruvate hydratase complex GO:0000015
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
1 Q27727 (/IMP)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q9C9C4 (/IDA)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 Q4QFL8 (/ISO)
External side of cell wall GO:0010339
The side of the cell wall that is opposite to the side that faces the cell and its contents.
1 Q45RT9 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 Q54RK5 (/HDA)