The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Met-10+ protein-like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: tRNA (guanine(37)-N1)-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA (guanine-N1-)-methyltransferase activity GO:0009019
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
8 P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) Q58293 (/IDA) Q9V0Q0 (/IDA) Q9V2G1 (/IDA)
TRNA (guanine-N1-)-methyltransferase activity GO:0009019
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
5 P38793 (/IMP) P38793 (/IMP) P38793 (/IMP) P38793 (/IMP) P38793 (/IMP)
TRNA (guanine-N1-)-methyltransferase activity GO:0009019
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
5 P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS)
TRNA (guanine(37)-N(1))-methyltransferase activity GO:0052906
Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.
1 Q8TFG7 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial tRNA methylation GO:0070901
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
6 F7GSQ4 (/ISS) F7GSQ4 (/ISS) F7GSQ4 (/ISS) Q3MHN8 (/ISS) Q95KJ2 (/ISS) Q9D0C4 (/ISS)
TRNA N1-guanine methylation GO:0002939
The process whereby a guanine in tRNA is methylated at position N1 of the guanine.
5 P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA)
TRNA N1-guanine methylation GO:0002939
The process whereby a guanine in tRNA is methylated at position N1 of the guanine.
5 P38793 (/IMP) P38793 (/IMP) P38793 (/IMP) P38793 (/IMP) P38793 (/IMP)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
5 P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS)
Mitochondrial tRNA methylation GO:0070901
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
5 P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
3 Q58293 (/IDA) Q9V0Q0 (/IDA) Q9V2G1 (/IDA)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
1 Q8TFG7 (/ISO)
Mitochondrial tRNA methylation GO:0070901
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
1 Q32P41 (/IMP)
Mitochondrial tRNA methylation GO:0070901
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
1 Q9D0C4 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
8 B8A5G9 (/ISS) F6VSS6 (/ISS) F7GSQ4 (/ISS) F7GSQ4 (/ISS) F7GSQ4 (/ISS) Q3MHN8 (/ISS) Q95KJ2 (/ISS) Q9D0C4 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P38793 (/HDA) P38793 (/HDA) P38793 (/HDA) P38793 (/HDA) P38793 (/HDA) Q8TFG7 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
6 P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) Q32P41 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS) P38793 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P38793 (/HDA) P38793 (/HDA) P38793 (/HDA) P38793 (/HDA) P38793 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA) P38793 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9D0C4 (/ISO)