The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Knottin, scorpion toxin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Alpha-like toxin BmK-M1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sodium channel inhibitor activity GO:0019871
Stops, prevents, or reduces the activity of a sodium channel.
5 C0HK69 (/IDA) O61705 (/IDA) P56612 (/IDA) P60214 (/IDA) P84646 (/IDA)
Sodium channel inhibitor activity GO:0019871
Stops, prevents, or reduces the activity of a sodium channel.
3 P60213 (/ISS) P60215 (/ISS) P60215 (/ISS)
Sodium channel inhibitor activity GO:0019871
Stops, prevents, or reduces the activity of a sodium channel.
3 B7FDP2 (/NAS) P15228 (/NAS) P83644 (/NAS)
Sodium channel regulator activity GO:0017080
Modulates the activity of a sodium channel.
1 P60212 (/IDA)
Potassium channel inhibitor activity GO:0019870
Stops, prevents, or reduces the activity of a potassium channel.
1 O61705 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
11 B7FDP2 (/IDA) E7CLP2 (/IDA) O61705 (/IDA) P15228 (/IDA) P56612 (/IDA) P60212 (/IDA) P60213 (/IDA) P60214 (/IDA) P83644 (/IDA) P84693 (/IDA)
(1 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
3 P60213 (/ISS) P60215 (/ISS) P60215 (/ISS)
Envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism GO:0044493
A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism.
2 C0HJM9 (/IDA) C0HJM9 (/IDA)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
1 P83644 (/IDA)
Modulation of sensory perception of pain in other organism GO:0044465
A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.
1 E7CAU3 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
10 B7FDP2 (/IDA) C0HJM9 (/IDA) C0HJM9 (/IDA) C0HK69 (/IDA) E7CAU3 (/IDA) E7CLP2 (/IDA) O61705 (/IDA) P15228 (/IDA) P56612 (/IDA) P84646 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
7 P60212 (/HDA) P60213 (/HDA) P60214 (/HDA) P60215 (/HDA) P60215 (/HDA) P84693 (/HDA) P84693 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P83644 (/NAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P08900 (/TAS)