The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TCP-1-like chaperonin intermediate domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: T-complex protein 1 subunit delta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
15 C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P50991 (/IPI) P50991 (/IPI) P50991 (/IPI) P50991 (/IPI) P50991 (/IPI) P80315 (/IPI) P80315 (/IPI) P80315 (/IPI)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
7 P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
5 P50991 (/HDA) P50991 (/HDA) P50991 (/HDA) P50991 (/HDA) P50991 (/HDA)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
5 P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
2 Q38CD4 (/ISA) Q38CD4 (/ISA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P50999 (/ISM)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
1 P50999 (/ISO)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
15 C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS) C0H5I7 (/ISS)
(5 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
7 P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA) P39078 (/IDA)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
5 P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
ScaRNA localization to Cajal body GO:0090666
A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
Positive regulation of establishment of protein localization to telomere GO:1904851
Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
Positive regulation of protein localization to Cajal body GO:1904871
Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.
5 P50991 (/HMP) P50991 (/HMP) P50991 (/HMP) P50991 (/HMP) P50991 (/HMP)
Positive regulation of telomerase RNA localization to Cajal body GO:1904874
Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
5 P50991 (/HMP) P50991 (/HMP) P50991 (/HMP) P50991 (/HMP) P50991 (/HMP)
Positive regulation of telomerase RNA localization to Cajal body GO:1904874
Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
5 P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP) P50991 (/IMP)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
3 P80315 (/IDA) P80315 (/IDA) P80315 (/IDA)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
ScaRNA localization to Cajal body GO:0090666
A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Toxin transport GO:1901998
The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 P80315 (/IMP) P80315 (/IMP) P80315 (/IMP)
Positive regulation of establishment of protein localization to telomere GO:1904851
Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Positive regulation of telomerase RNA localization to Cajal body GO:1904874
Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 Q6P123 (/IDA) Q6PH46 (/IDA)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
2 Q38CD4 (/ISA) Q38CD4 (/ISA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9LV21 (/IEP) Q9LV21 (/IEP)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
2 Q38CD4 (/ISA) Q38CD4 (/ISA)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
1 P50999 (/ISO)
Post-embryonic body morphogenesis GO:0040032
The process in which the anatomical structures of the post-embryonic soma are generated and organized.
1 P47208 (/IMP)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
31 C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA) C0H5I7 (/IDA)
(21 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
7 P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) Q9LV21 (/IDA) Q9LV21 (/IDA)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
7 P39078 (/IPI) P39078 (/IPI) P39078 (/IPI) P39078 (/IPI) P39078 (/IPI) P39078 (/IPI) P39078 (/IPI)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
5 P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
5 P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS) P50991 (/TAS)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
5 P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA) P50991 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P50991 (/HDA) P50991 (/HDA) P50991 (/HDA) P50991 (/HDA) P50991 (/HDA)
Zona pellucida receptor complex GO:0002199
A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.
3 P80315 (/IDA) P80315 (/IDA) P80315 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
3 Q54CL2 (/ISS) Q5R637 (/ISS) Q7TPB1 (/ISS)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
3 P80315 (/ISO) P80315 (/ISO) P80315 (/ISO)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
3 P80315 (/IDA) P80315 (/IDA) P80315 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q38CD4 (/IDA) Q38CD4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P50999 (/HDA) Q9VK69 (/HDA)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
2 Q38CD4 (/ISA) Q38CD4 (/ISA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P50999 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4QC87 (/ISO)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
1 P50999 (/ISO)