The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TruD, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: TruD, catalytic domain

Structural domains comprising this superfamily share the structure of the catalytic domain of TruD, a large family of pseudouridine synthase which are present in all kingdoms of life. Pseudouridine synthases catalyse the isomerisation of uridine to pseudouridine in structural RNA and TruD specifically modifies U13 in tRNA PMID:15135053.

GO Diversity

Unique GO annotations
23 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
4379 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 7
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 4
Alignments
Structural Clusters (5A): 2
Structural Clusters (9A): 2
FunFam Clusters: 81
Function
Unique EC: 1
Unique GO: 23
Taxonomy
Unique Species: 4379
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