The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
RelE-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: mRNA interferase toxin RelE

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
79 P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP)
(69 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
79 P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI)
(69 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
79 P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP)
(69 more)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
79 P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI)
(69 more)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
79 P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI)
(69 more)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
7 Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
79 P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP) P0C077 (/IEP)
(69 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
79 P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP)
(69 more)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
7 Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS) Q87UB8 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
79 P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA) P0C077 (/IDA)
(69 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
79 P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP) P0C077 (/IMP)
(69 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
79 P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI) P0C077 (/IPI)
(69 more)