The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"RelE-like
".
FunFam 11: Endoribonuclease HigB
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q7A225 (/IPI) Q7A225 (/IPI) |
|
Translation repressor activity GO:0030371
Antagonizes ribosome-mediated translation of mRNA into a polypeptide.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
2 | Q7A225 (/IMP) Q7A225 (/IMP) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA cleavage GO:0006379
Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
|
RNA phosphodiester bond hydrolysis, endonucleolytic GO:0090502
The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
2 | Q7A225 (/IDA) Q7A225 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.