The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 60: Serine/threonine-protein kinase isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine/tyrosine kinase activity GO:0004712
Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
15 F4IAN2 (/ISS) F4IAN2 (/ISS) F4JQX7 (/ISS) F4JTP5 (/ISS) O22558 (/ISS) Q05609 (/ISS) Q05609 (/ISS) Q8RWL6 (/ISS) Q8S9K4 (/ISS) Q9C9U5 (/ISS)
(5 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
9 F4JTP5 (/IDA) O22558 (/IDA) Q05609 (/IDA) Q05609 (/IDA) Q2MHE4 (/IDA) Q2MHE4 (/IDA) Q8RWL6 (/IDA) Q9ZQ31 (/IDA) Q9ZQ31 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q05609 (/IPI) Q05609 (/IPI) Q2MHE4 (/IPI) Q2MHE4 (/IPI) Q54H46 (/IPI) Q9C9U5 (/IPI) Q9FPR3 (/IPI)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
3 Q2MHE4 (/IDA) Q2MHE4 (/IDA) Q54H46 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
2 Q2MHE4 (/IMP) Q2MHE4 (/IMP)
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
2 Q9ZQ31 (/IDA) Q9ZQ31 (/IDA)
MAP kinase kinase kinase activity GO:0004709
Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
1 Q9FPR3 (/IMP)
MAP kinase kinase kinase activity GO:0004709
Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
1 Q9FPR3 (/ISS)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 Q9FPR3 (/IDA)

There are 38 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
5 Q05609 (/IDA) Q05609 (/IDA) Q2MHE4 (/IDA) Q2MHE4 (/IDA) Q9FPR3 (/IDA)
Chloroplast organization GO:0009658
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
3 F4JTP5 (/IGI) O22558 (/IGI) Q8RWL6 (/IGI)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
3 Q05609 (/IMP) Q05609 (/IMP) Q9FPR3 (/IMP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 Q05609 (/IMP) Q05609 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q9ZQ31 (/IDA) Q9ZQ31 (/IDA)
Gibberellin biosynthetic process GO:0009686
The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
2 Q05609 (/IMP) Q05609 (/IMP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
2 Q05609 (/IMP) Q05609 (/IMP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
2 Q05609 (/IMP) Q05609 (/IMP)
Root epidermal cell differentiation GO:0010053
The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.
2 Q9M085 (/IMP) Q9M085 (/IMP)
Negative regulation of ethylene-activated signaling pathway GO:0010105
Any process that stops or prevents ethylene (ethene) signal transduction.
2 Q05609 (/TAS) Q05609 (/TAS)
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
2 Q2MHE4 (/IDA) Q2MHE4 (/IDA)
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
2 Q2MHE4 (/IMP) Q2MHE4 (/IMP)
Sugar mediated signaling pathway GO:0010182
The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
2 Q05609 (/TAS) Q05609 (/TAS)
Seed oilbody biogenesis GO:0010344
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.
2 Q9ZQ31 (/IMP) Q9ZQ31 (/IMP)
Regulation of embryonic development GO:0045995
Any process that modulates the frequency, rate or extent of embryonic development.
2 Q9ZQ31 (/IGI) Q9ZQ31 (/IGI)
Regulation of timing of transition from vegetative to reproductive phase GO:0048510
The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
2 Q05609 (/IMP) Q05609 (/IMP)
Cellular response to carbon dioxide GO:0071244
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
2 Q2MHE4 (/IDA) Q2MHE4 (/IDA)
Cellular response to carbon dioxide GO:0071244
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
2 Q2MHE4 (/IMP) Q2MHE4 (/IMP)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
2 Q05609 (/IEP) Q05609 (/IEP)
Regulation of stomatal closure GO:0090333
Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
2 Q2MHE4 (/IMP) Q2MHE4 (/IMP)
Regulation of response to red or far red light GO:2000030
Any process that modulates the frequency, rate or extent of response to red or far red light.
2 Q2MHE4 (/IDA) Q2MHE4 (/IDA)
Regulation of stem cell division GO:2000035
Any process that modulates the frequency, rate or extent of stem cell division.
2 Q05609 (/IMP) Q05609 (/IMP)
Regulation of post-embryonic root development GO:2000069
Any process that modulates the frequency, rate or extent of post-embryonic root development.
2 Q05609 (/IMP) Q05609 (/IMP)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
1 Q9FPR3 (/ISS)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
1 Q90458 (/IGI)
Defense response to oomycetes GO:0002229
Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
1 Q9FPR3 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q54H46 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q90458 (/IMP)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 Q9FPR3 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
1 Q9FPR3 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q9FPR3 (/IMP)
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
1 Q9FPR3 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q9C9U5 (/IMP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
1 Q9FPR3 (/IMP)
Sugar mediated signaling pathway GO:0010182
The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
1 Q9C9U5 (/IMP)
Regulation of defense response to fungus GO:1900150
Any process that modulates the frequency, rate or extent of defense response to fungus.
1 Q9FPR3 (/IMP)
Regulation of defense response to bacterium GO:1900424
Any process that modulates the frequency, rate or extent of defense response to bacterium.
1 Q9FPR3 (/IMP)
Regulation of salicylic acid mediated signaling pathway GO:2000031
Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.
1 Q9FPR3 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 F4IAN2 (/IDA) F4IAN2 (/IDA) Q2MHE4 (/IDA) Q2MHE4 (/IDA) Q8S9K4 (/IDA) Q9FPR3 (/IDA) Q9ZQ31 (/IDA) Q9ZQ31 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 F4JTP5 (/IDA) O22558 (/IDA) Q8RWL6 (/IDA) Q9FPR3 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9C9U5 (/IDA) Q9FPR3 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q05609 (/IDA) Q05609 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 Q9FPR3 (/IDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q9FPR3 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9FPR3 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
1 Q9FPR3 (/IDA)
Trans-Golgi network transport vesicle membrane GO:0012510
The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
1 Q9FPR3 (/IDA)