The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 455: Non-specific serine/threonine protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q24496 (/IPI) Q86NP0 (/IPI) Q9V3I5 (/IPI) Q9V3I5 (/IPI) Q9VR61 (/IPI)
Ribosomal protein S6 kinase activity GO:0004711
Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.
3 Q24496 (/IDA) Q86NP0 (/IDA) Q9VR61 (/IDA)
Ribosomal protein S6 kinase activity GO:0004711
Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.
3 Q24496 (/ISS) Q86NP0 (/ISS) Q9VR61 (/ISS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 Q9V3I5 (/ISS) Q9V3I5 (/ISS)
Histone kinase activity (H3-S10 specific) GO:0035175
Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Histone kinase activity (H3-S10 specific) GO:0035175
Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.
2 Q9V3I5 (/TAS) Q9V3I5 (/TAS)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
3 Q24496 (/ISS) Q86NP0 (/ISS) Q9VR61 (/ISS)
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Associative learning GO:0008306
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Operant conditioning GO:0035106
Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Negative regulation of protein import into nucleus GO:0042308
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.
3 Q24496 (/IDA) Q86NP0 (/IDA) Q9VR61 (/IDA)
Negative regulation of compound eye cone cell fate specification GO:0042683
Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Negative regulation of photoreceptor cell differentiation GO:0046533
Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
3 Q24496 (/IGI) Q86NP0 (/IGI) Q9VR61 (/IGI)
Negative regulation of pigment cell differentiation GO:0050941
Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Regulation of neuromuscular junction development GO:1904396
Any process that modulates the frequency, rate or extent of neuromuscular junction development.
3 Q24496 (/IMP) Q86NP0 (/IMP) Q9VR61 (/IMP)
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
2 Q9V3I5 (/TAS) Q9V3I5 (/TAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Female meiosis chromosome segregation GO:0016321
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
2 Q9V3I5 (/HMP) Q9V3I5 (/HMP)
Histone phosphorylation GO:0016572
The modification of histones by addition of phosphate groups.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Histone phosphorylation GO:0016572
The modification of histones by addition of phosphate groups.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Histone phosphorylation GO:0016572
The modification of histones by addition of phosphate groups.
2 Q9V3I5 (/TAS) Q9V3I5 (/TAS)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Negative regulation of chromatin silencing GO:0031936
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)
Chromosome organization GO:0051276
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
2 Q9V3I5 (/IMP) Q9V3I5 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
3 Q24496 (/IDA) Q86NP0 (/IDA) Q9VR61 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
3 Q24496 (/IDA) Q86NP0 (/IDA) Q9VR61 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
3 Q24496 (/IDA) Q86NP0 (/IDA) Q9VR61 (/IDA)
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9V3I5 (/HDA) Q9V3I5 (/HDA)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Polytene chromosome puff GO:0005703
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
Polytene chromosome interband GO:0005705
A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.
2 Q9V3I5 (/IDA) Q9V3I5 (/IDA)
X chromosome located dosage compensation complex, transcription activating GO:0016456
An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.
2 Q9V3I5 (/IPI) Q9V3I5 (/IPI)