The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 367: Protein kinase C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 28 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase C activity GO:0004697
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
8 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P68403 (/IDA) P68403 (/IDA) P68404 (/IDA) P68404 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P05771 (/IPI) P05771 (/IPI) P05771 (/IPI) P05771 (/IPI) P68403 (/IPI) P68403 (/IPI) P68404 (/IPI) P68404 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Histone kinase activity (H3-T6 specific) GO:0035403
Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4 P05771 (/EXP) P05771 (/EXP) P05771 (/EXP) P05771 (/EXP)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Protein kinase C activity GO:0004697
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
4 P05771 (/IPI) P05771 (/IPI) P05771 (/IPI) P05771 (/IPI)
Nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
4 P05771 (/IMP) P05771 (/IMP) P05771 (/IMP) P05771 (/IMP)
Histone kinase activity (H3-T6 specific) GO:0035403
Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 P68404 (/ISO) P68404 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 P68404 (/IDA) P68404 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 P68404 (/ISO) P68404 (/ISO)
Protein kinase C activity GO:0004697
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
2 P68404 (/ISO) P68404 (/ISO)
Protein kinase C activity GO:0004697
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
2 P05126 (/ISS) P05772 (/ISS)
Protein kinase C binding GO:0005080
Interacting selectively and non-covalently with protein kinase C.
2 P68404 (/ISO) P68404 (/ISO)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
2 P68404 (/IDA) P68404 (/IDA)
Nuclear receptor transcription coactivator activity GO:0030374
The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
2 P68404 (/ISO) P68404 (/ISO)
Histone kinase activity (H3-T6 specific) GO:0035403
Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.
2 P68404 (/ISO) P68404 (/ISO)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
2 P68404 (/ISO) P68404 (/ISO)
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
2 P68404 (/ISO) P68404 (/ISO)
Protein kinase C activity GO:0004697
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
1 A0A1D5PCZ1 (/IMP)

There are 55 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of glucose transmembrane transport GO:0010829
Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949
Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Negative regulation of insulin receptor signaling pathway GO:0046627
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68404 (/ISS) P68404 (/ISS)
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Positive regulation of B cell receptor signaling pathway GO:0050861
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
8 P05126 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05771 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Regulation of glucose transmembrane transport GO:0010827
Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Histone H3-T6 phosphorylation GO:0035408
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 P05771 (/IMP) P05771 (/IMP) P05771 (/IMP) P05771 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
4 P05771 (/NAS) P05771 (/NAS) P05771 (/NAS) P05771 (/NAS)
Regulation of glucose transmembrane transport GO:0010827
Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Histone H3-T6 phosphorylation GO:0035408
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Lipoprotein transport GO:0042953
The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Regulation of myeloid cell differentiation GO:0045637
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
3 A0A1D5PCZ1 (/IMP) P68404 (/IMP) P68404 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P68404 (/ISO) P68404 (/ISO)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P68404 (/IDA) P68404 (/IDA)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P68404 (/IDA) P68404 (/IDA)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
2 P68404 (/IDA) P68404 (/IDA)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 P68403 (/IEP) P68403 (/IEP)
Negative regulation of glucose transmembrane transport GO:0010829
Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P68404 (/IMP) P68404 (/IMP)
Regulation of dopamine secretion GO:0014059
Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
2 P68403 (/IMP) P68403 (/IMP)
Regulation of dopamine secretion GO:0014059
Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
2 P68404 (/ISO) P68404 (/ISO)
Dibenzo-p-dioxin metabolic process GO:0018894
The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.
2 P68403 (/IEP) P68403 (/IEP)
Positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949
Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
2 P68404 (/IMP) P68404 (/IMP)
Response to vitamin D GO:0033280
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
2 P68403 (/IEP) P68403 (/IEP)
Histone H3-T6 phosphorylation GO:0035408
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.
2 P68404 (/ISO) P68404 (/ISO)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2 P68403 (/NAS) P68403 (/NAS)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
2 P68403 (/IMP) P68403 (/IMP)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
2 P68404 (/ISO) P68404 (/ISO)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2 P68404 (/IMP) P68404 (/IMP)
Positive regulation of odontogenesis of dentin-containing tooth GO:0042488
Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
2 P68403 (/IEP) P68403 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 P68403 (/IMP) P68403 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 P68404 (/ISO) P68404 (/ISO)
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
2 P68404 (/IMP) P68404 (/IMP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 P68403 (/IEP) P68403 (/IEP)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
2 P68404 (/IMP) P68404 (/IMP)
Negative regulation of insulin receptor signaling pathway GO:0046627
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
2 P68403 (/IDA) P68403 (/IDA)
Negative regulation of insulin receptor signaling pathway GO:0046627
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
2 P68404 (/ISO) P68404 (/ISO)
Positive regulation of B cell receptor signaling pathway GO:0050861
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
2 P68404 (/IMP) P68404 (/IMP)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
2 P68404 (/IMP) P68404 (/IMP)
Cellular response to carbohydrate stimulus GO:0071322
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
2 P68404 (/IDA) P68404 (/IDA)
Presynaptic modulation of chemical synaptic transmission GO:0099171
Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.
2 P68404 (/IDA) P68404 (/IDA)
Presynaptic modulation of chemical synaptic transmission GO:0099171
Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.
2 P68404 (/IMP) P68404 (/IMP)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 P68404 (/IDA) P68404 (/IDA)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 P68404 (/IMP) P68404 (/IMP)
I-kappaB kinase/NF-kappaB signaling GO:0007249
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
1 A0A1D5PCZ1 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 A0A1D5PCZ1 (/IMP)

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P68404 (/IDA) P68404 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P05126 (/ISS) P05772 (/ISS) P68403 (/ISS) P68403 (/ISS) P68404 (/ISS) P68404 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P68404 (/IDA) P68404 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P68403 (/IDA) P68403 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P68403 (/IDA) P68403 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 P05771 (/IDA) P05771 (/IDA) P05771 (/IDA) P05771 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P05771 (/TAS) P05771 (/TAS) P05771 (/TAS) P05771 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 P05771 (/HDA) P05771 (/HDA) P05771 (/HDA) P05771 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P68404 (/ISO) P68404 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P68404 (/ISO) P68404 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P68404 (/ISO) P68404 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 P68403 (/IDA) P68403 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 P68404 (/ISO) P68404 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P68404 (/ISO) P68404 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P68404 (/ISO) P68404 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
2 P68403 (/IDA) P68403 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
2 P68404 (/ISO) P68404 (/ISO)
Calyx of Held GO:0044305
The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
2 P68404 (/IDA) P68404 (/IDA)
Calyx of Held GO:0044305
The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
2 P68404 (/IMP) P68404 (/IMP)
Presynaptic cytosol GO:0099523
The region of the cytosol consisting of all cytosol that is part of the presynapse.
2 P68404 (/IDA) P68404 (/IDA)