The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 143: Ephrin type-B receptor 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transmembrane-ephrin receptor activity GO:0005005
Combining with a transmembrane ephrin to initiate a change in cell activity.
8 D1YSF9 (/ISS) O96435 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q8IMC2 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O09127 (/IPI) Q5JZY3 (/IPI)
Ephrin receptor activity GO:0005003
Combining with an ephrin to initiate a change in cell activity.
1 O15197 (/TAS)
GPI-linked ephrin receptor activity GO:0005004
Combining with a GPI-anchored ephrin to initiate a change in cell activity.
1 O09127 (/IDA)
GPI-linked ephrin receptor activity GO:0005004
Combining with a GPI-anchored ephrin to initiate a change in cell activity.
1 P29322 (/ISS)
Transmembrane-ephrin receptor activity GO:0005005
Combining with a transmembrane ephrin to initiate a change in cell activity.
1 Q8BYG9 (/ISO)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
1 O15197 (/TAS)

There are 31 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
9 D1YSF9 (/ISS) O96435 (/ISS) P29322 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q8IMC2 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
9 D1YSF9 (/ISS) O96435 (/ISS) P29322 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q8IMC2 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
8 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q8IMC2 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
8 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q8IMC2 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
8 D1YSF9 (/IMP) O96435 (/IMP) Q0KIF4 (/IMP) Q59DQ4 (/IMP) Q8IMC2 (/IMP) Q9V4E5 (/IMP) Q9XZL6 (/IMP) Q9Y1J0 (/IMP)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
3 O15197 (/TAS) P29322 (/TAS) Q5JZY3 (/TAS)
Type IV hypersensitivity GO:0001806
An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.
1 O08644 (/IMP)
T cell mediated immunity GO:0002456
Any process involved in the carrying out of an immune response by a T cell.
1 O08644 (/IMP)
Substrate-dependent cell migration GO:0006929
The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
1 O09127 (/IDA)
Substrate-dependent cell migration GO:0006929
The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
1 P29322 (/ISS)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 O09127 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 P29322 (/ISS)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
1 O09127 (/IDA)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
1 P29322 (/ISS)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
1 O09127 (/IDA)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
1 P29322 (/ISS)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 O09127 (/IDA)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 P29322 (/ISS)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 O08644 (/IMP)
Regulation of cell adhesion mediated by integrin GO:0033628
Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
1 O09127 (/IDA)
Regulation of cell adhesion mediated by integrin GO:0033628
Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
1 P29322 (/ISS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 O09127 (/IDA)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
1 P29322 (/ISS)
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
1 O09127 (/IDA)
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
1 P29322 (/ISS)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 O09127 (/IDA)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
1 O09127 (/IDA)
Cytokine secretion GO:0050663
The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
1 O08644 (/IMP)
Activated T cell proliferation GO:0050798
The expansion of a T cell population following activation by an antigenic stimulus.
1 O08644 (/IMP)
Cellular response to follicle-stimulating hormone stimulus GO:0071372
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
1 O09127 (/IDA)
Positive regulation of T cell costimulation GO:2000525
Any process that activates or increases the frequency, rate or extent of T cell costimulation.
1 O08644 (/IGI)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
9 D1YSF9 (/ISS) O96435 (/ISS) P29322 (/ISS) Q0KIF4 (/ISS) Q59DQ4 (/ISS) Q8IMC2 (/ISS) Q9V4E5 (/ISS) Q9XZL6 (/ISS) Q9Y1J0 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 O15197 (/TAS) P29322 (/TAS) Q5JZY3 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 O15197 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O15197 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 O09127 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 O08644 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 O09127 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P29322 (/ISS)