The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 118: Non-specific serine/threonine protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
36 A4GW50 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI)
(26 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
34 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(24 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
30 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(20 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
30 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(20 more)
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
26 Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI) Q15208 (/IPI)
(16 more)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
26 Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA) Q15208 (/HDA)
(16 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
8 Q2L6W9 (/ISS) Q5ZLR3 (/ISS) Q7TSE6 (/ISS) Q91VJ4 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
8 Q2L6W9 (/ISS) Q5ZLR3 (/ISS) Q7TSE6 (/ISS) Q91VJ4 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 Q5ZLR3 (/ISS) Q7TSE6 (/ISS) Q91VJ4 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
1 Q91VJ4 (/ISO)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
34 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(24 more)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
34 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(24 more)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
28 A2VDV2 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS)
(18 more)
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
26 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(16 more)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
26 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(16 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
8 Q2L6W9 (/ISS) Q5ZLR3 (/ISS) Q7TSE6 (/ISS) Q91VJ4 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
7 Q5ZLR3 (/ISS) Q7TSE6 (/ISS) Q91VJ4 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS)
Regulation of cellular component organization GO:0051128
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
5 Q5ZLR3 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Imaginal disc-derived wing hair organization GO:0035317
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Antennal morphogenesis GO:0048800
The process in which the anatomical structures of the antenna are generated and organized.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Regulation of dendrite development GO:0050773
Any process that modulates the frequency, rate or extent of dendrite development.
4 Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP) Q9NBK5 (/IMP)
Dendrite self-avoidance GO:0070593
The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
4 Q9NBK5 (/IGI) Q9NBK5 (/IGI) Q9NBK5 (/IGI) Q9NBK5 (/IGI)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
1 Q91VJ4 (/ISO)
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
1 Q5ZLR3 (/ISS)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
1 Q2L6W9 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
1 Q2L6W9 (/IMP)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
1 Q2L6W9 (/IMP)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
1 Q2L6W9 (/IMP)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q2L6W9 (/IMP)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
1 Q91VJ4 (/ISO)
Regulation of cellular component organization GO:0051128
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 Q7TSE6 (/IDA)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
56 A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA) A0A024RD18 (/IDA)
(46 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
36 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(26 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
31 Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA) Q15208 (/IDA)
(21 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
29 A2VDV2 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS) Q5R8M1 (/ISS)
(19 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q5ZLR3 (/ISS) Q91VJ4 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS) Q9NBK5 (/ISS)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
5 Q5ZLR3 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS) Q9Y2H1 (/ISS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
5 Q2L6W9 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
5 Q2L6W9 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
4 Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
4 Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Cell hair GO:0070451
A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.
4 Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
4 Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA) Q9NBK5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q7TSE6 (/ISO) Q91VJ4 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q91VJ4 (/ISO)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 Q7TSE6 (/IDA)