The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 931: zinc finger protein 697

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
11 Q9VDQ3 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VJL7 (/ISS)
(1 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
11 Q9VDQ3 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VJL7 (/ISS)
(1 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
6 Q9VGL2 (/IDA) Q9VGL2 (/IDA) Q9VGL2 (/IDA) Q9VGL2 (/IDA) R9PY35 (/IDA) R9PY35 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q9VJL7 (/ISS) Q9VJL7 (/ISS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q5TEC3 (/ISA)
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
1 Q8BU41 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q8BU41 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
11 Q9VDQ3 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VJL7 (/ISS)
(1 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q8BU41 (/IMP)
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
1 Q8BU41 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9VDQ3 (/IMP)
Regulation of DNA methylation GO:0044030
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
1 Q8BU41 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q8BU41 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 Q9VDQ3 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VDQ6 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VGL2 (/ISS) Q9VJL7 (/ISS)
(3 more)