The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Classic Zinc Finger
".
FunFam 34: zinc finger protein 25
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
84 |
A6NP11 (/ISA)
A6NP11 (/ISA)
A6NP11 (/ISA)
A6NP11 (/ISA)
A6NP11 (/ISA)
A6NP11 (/ISA)
B4DXR9 (/ISA)
B4DXR9 (/ISA)
B4DXR9 (/ISA)
B4DXR9 (/ISA)
(74 more) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
15 |
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
(5 more) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
14 |
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
(4 more) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
14 |
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
(4 more) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
12 |
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
O75346 (/NAS)
Q03938 (/NAS)
Q03938 (/NAS)
(2 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | Q7L2R6 (/IPI) Q7L2R6 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) Q8IW36 (/IPI) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
4 | Q03938 (/NAS) Q03938 (/NAS) Q03938 (/NAS) Q03938 (/NAS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) O75346 (/NAS) |
|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
2 | Q15928 (/TAS) Q15928 (/TAS) |
|
Anatomical structure morphogenesis GO:0009653
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
|
2 | Q15928 (/TAS) Q15928 (/TAS) |
|
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
|
2 | Q15928 (/IMP) Q15928 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
14 |
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
Q03923 (/IDA)
(4 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
14 |
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
Q03923 (/TAS)
(4 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q3UY47 (/ISO) Q5U406 (/ISO) Q69ZK4 (/ISO) Q8BJ21 (/ISO) |