The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Classic Zinc Finger
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: zinc finger protein 615 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
74 B4DU55 (/ISA) B4DU55 (/ISA) O43296 (/ISA) O43296 (/ISA) O43296 (/ISA) O60765 (/ISA) O60765 (/ISA) O60765 (/ISA) O60765 (/ISA) O60765 (/ISA)
(64 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
18 Q08ER8 (/IPI) Q08ER8 (/IPI) Q08ER8 (/IPI) Q14C61 (/IPI) Q14C61 (/IPI) Q14C61 (/IPI) Q6NX49 (/IPI) Q6NX49 (/IPI) Q86WZ6 (/IPI) Q86WZ6 (/IPI)
(8 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
4 G3V9G6 (/NAS) G3V9G6 (/NAS) Q62788 (/NAS) Q62788 (/NAS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
4 Q9QXT9 (/IDA) Q9QXT9 (/IDA) Q9QXT9 (/IDA) Q9QXT9 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q7TNU6 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
8 O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
8 O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS) O60765 (/TAS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 Q9QXT9 (/IDA) Q9QXT9 (/IDA) Q9QXT9 (/IDA) Q9QXT9 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
4 Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
4 Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
4 Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP)
Nucleolar fragmentation GO:0007576
The cell aging process that results in the nucleolus breaking down into fragments.
4 Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP) Q02975 (/IMP)
Nucleolar fragmentation GO:0007576
The cell aging process that results in the nucleolus breaking down into fragments.
4 Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
4 G3V9G6 (/IDA) G3V9G6 (/IDA) Q62788 (/IDA) Q62788 (/IDA)
Response to folic acid GO:0051593
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
4 Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP) Q02975 (/IEP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 P10072 (/NAS) P10072 (/NAS)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2 P10072 (/NAS) P10072 (/NAS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
22 O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) Q02975 (/IDA) Q02975 (/IDA)
(12 more)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
20 O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) Q02975 (/IDA) Q02975 (/IDA)
(10 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
17 A0A087WRR7 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q69Z88 (/ISO) Q69Z88 (/ISO) Q69Z88 (/ISO) Q69Z88 (/ISO) Q69Z88 (/ISO)
(7 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
16 O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) O60765 (/IDA) V9HWI2 (/IDA) V9HWI2 (/IDA)
(6 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 O60765 (/HDA) O60765 (/HDA) O60765 (/HDA) O60765 (/HDA) O60765 (/HDA) O60765 (/HDA) O60765 (/HDA) O60765 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q61751 (/ISS) Q61751 (/ISS) Q61751 (/ISS) Q61751 (/ISS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
4 Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO) Q61751 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
2 Q8NA42 (/IDA) Q8NA42 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 A0A087WRR7 (/ISO)