The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Exonuclease ExoI, domain 2

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Exodeoxyribonuclease I

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Exodeoxyribonuclease I. [EC:]
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
  • Preference for single-stranded DNA.
  • The Escherichia coli enzyme hydrolyzes glucosylated DNA.
  • Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases.
  • Formerly EC
40 A0A069XVI1 A0A069XVI1 A0A069XVI1 A0A069XVI1 A0A069XVI1 A0A069XVI1 A0A070SM66 A0A070SM66 A0A070SM66 A0A070SM66
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