The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein L5

This superfamily includes the ribosomal protein L5 from the large subunit of the eubacterial, algal chloroplast, cyanelle, plant mitochondrial and archaebacterial ribosome. The entry also includes its homologues, mammalian L11, Tetrahymena thermophila L21, Dictyostelium discoideum (Slime mold) L5, Saccharomyces cerevisiae (Baker's yeast) L16 (39A). Members of the PFAM:UPF0201/DUF54 family are also predicted to be evolutionarily related to this superfamily.

The structural domain comprises five-stranded antiparallel beta-sheet and four alpha-helices, which fold in a way that is topologically similar to the ribonucleoprotein (RNP) domain. The molecule has a ribo-nucleoprotein (RNP) motif for RNA recognition.

In Escherichia coli, L5 is known to be involved in binding 5S RNA, forming a complex along with 2 other ribosomal proteins, L18 and L25. L5 is the primary 5S rRNA binding protein.

PFAM:PF00673, INTERPRO:IPR022803,PMID:11350033,PMID:19079550

GO Diversity

Unique GO annotations
65 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
18751 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 404
Domain clusters (>95% seq id): 19
Domain clusters (>35% seq id): 8
Unique PDBs: 392
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 16
Unique EC:
Unique GO: 65
Unique Species: 18751