The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"K Homology domain, type 1
".
FunFam 30: KH domain-containing, RNA-binding, signal transduc...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
O75525 (/IPI)
O75525 (/IPI)
O75525 (/IPI)
O75525 (/IPI)
O75525 (/IPI)
O75525 (/IPI)
Q5VWX1 (/IPI)
Q5VWX1 (/IPI)
Q5VWX1 (/IPI)
Q920F3 (/IPI)
(2 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
6 | O75525 (/HDA) O75525 (/HDA) O75525 (/HDA) O75525 (/HDA) O75525 (/HDA) O75525 (/HDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
6 | O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
6 | O75525 (/IPI) O75525 (/IPI) O75525 (/IPI) O75525 (/IPI) O75525 (/IPI) O75525 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
6 | O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | Q5VWX1 (/IPI) Q5VWX1 (/IPI) Q5VWX1 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q9JLP1 (/ISS) Q9R226 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q9R226 (/ISO) Q9WU01 (/ISO) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9R226 (/ISO) |
|
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
|
1 | Q9JLP1 (/IDA) |
|
Single-stranded RNA binding GO:0003727
Interacting selectively and non-covalently with single-stranded RNA.
|
1 | Q9R226 (/ISO) |
|
SH3/SH2 adaptor activity GO:0005070
Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
|
1 | Q9WU01 (/TAS) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
1 | Q9WU01 (/IDA) |
|
Poly(U) RNA binding GO:0008266
Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule.
|
1 | Q9WU01 (/IDA) |
|
SH3 domain binding GO:0017124
Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
|
1 | Q9WU01 (/IDA) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | Q9R226 (/ISO) |
|
SH2 domain binding GO:0042169
Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.
|
1 | Q9WU01 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q9WU01 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
6 | O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) |
|
Regulation of mRNA splicing, via spliceosome GO:0048024
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
|
2 | Q9R226 (/IDA) Q9WU01 (/IDA) |
|
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
|
1 | Q9JLP1 (/IDA) |
|
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
|
1 | Q9R226 (/ISO) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q9JLP1 (/IEP) |
|
Positive regulation of RNA splicing GO:0033120
Any process that activates or increases the frequency, rate or extent of RNA splicing.
|
1 | Q9JLP1 (/IMP) |
|
Positive regulation of RNA splicing GO:0033120
Any process that activates or increases the frequency, rate or extent of RNA splicing.
|
1 | Q9R226 (/ISO) |
|
Protein complex oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q9R226 (/ISO) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
9 | E5RJZ9 (/IDA) E5RJZ9 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) O75525 (/IDA) Q9R226 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
9 | O75525 (/TAS) O75525 (/TAS) O75525 (/TAS) O75525 (/TAS) O75525 (/TAS) O75525 (/TAS) Q5VWX1 (/TAS) Q5VWX1 (/TAS) Q5VWX1 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | O75525 (/IMP) O75525 (/IMP) O75525 (/IMP) O75525 (/IMP) O75525 (/IMP) O75525 (/IMP) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9JLP1 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9R226 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9WU01 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9R226 (/ISO) |