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CATH Superfamily 3.30.1360.40

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA topoisomerase (ATP-hydrolyzing). [EC: 5.6.2.3]
ATP-dependent breakage, passage and rejoining of double-stranded DNA.
  • The enzyme can introduce negative superhelical turns into double- stranded circular DNA.
  • One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of ATP (cf. EC 5.6.2.2).
  • Formerly EC 5.99.1.3.
 488 A0A023ZX05 A0A026UKE4 A0A028APL5 A0A028E7F9 A0A069ZX90 A0A070FDW0 A0A070FEW1 A0A070SN88 A0A070SVW8 A0A070V0R4
(478 more...)
5-oxoprolinase (ATP-hydrolyzing). [EC: 3.5.2.9]
ATP + 5-oxo-L-proline + 2 H(2)O = ADP + phosphate + L-glutamate.
    		 5 A0A164U4B9 A0A1B2B282 G4EZY2 L8AAZ8 P60495
    Urea carboxylase. [EC: 6.3.4.6]
    ATP + urea + HCO(3)(-) = ADP + phosphate + urea-1-carboxylate.
    • The Saccharomyces cerevisiae enzyme (but not that from green algae) also catalyzes the reaction of EC 3.5.1.54, thus bringing about the hydrolysis of urea to CO(2) and NH(3).
    • The enzyme from the prokaryotic bacterium Oleomonas sagaranensis can also use acetamide and formamide as substrates.
    • Formerly EC 3.5.1.45.
    		 4 A5H0J2 C7GKH0 P32528 P38095
    Allophanate hydrolase. [EC: 3.5.1.54]
    Urea-1-carboxylate + H(2)O = 2 CO(2) + 2 NH(3).
    • Along with EC 3.5.2.15 and EC 3.5.1.84, forms part of the cyanuric- acid metabolism pathway, which degrades s-triazide herbicides, such as atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5- triazine), in bacteria.
    • The Saccharomyces cerevisiae enzyme (but not that from green algae) also catalyzes the reaction of EC 6.3.4.6, thus bringing about the hydrolysis of urea to CO(2) and NH(3) in the presence of ATP and bicarbonate.
    • The enzyme from Pseudomonas sp. strain ADP has a narrow substrate specificity, being unable to use the structurally analogous compounds urea, hydroxyurea or methylcarbamate as substrate.
    		 3 A5H0J2 C7GKH0 P32528