The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 87: Anaerobic ribonucleoside-triphosphate reductase-ac...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
56 P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI) P0A9N8 (/IPI)
(46 more)
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
56 P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA)
(46 more)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
56 P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA) P0A9N8 (/IDA)
(46 more)
Ribonucleoside-triphosphate reductase activity GO:0008998
Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
8 Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
56 P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP)
(46 more)
2'-deoxyribonucleotide biosynthetic process GO:0009265
The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
8 Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS) Q9KM76 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anaerobic ribonucleoside-triphosphate reductase complex GO:0031250
An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.
56 P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP) P0A9N8 (/IMP)
(46 more)