The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56: hydroxyacid oxidase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
(S)-2-hydroxy-acid oxidase activity GO:0003973
Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
9 Q07523 (/IDA) Q9NYQ3 (/IDA) Q9NYQ3 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9WU19 (/IDA) Q9WU19 (/IDA)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
5 Q07523 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA)
Glycolate oxidase activity GO:0008891
Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide.
4 Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA)
(S)-2-hydroxy-acid oxidase activity GO:0003973
Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
3 Q9NYQ2 (/ISO) Q9WU19 (/ISO) Q9WU19 (/ISO)
(S)-2-hydroxy-acid oxidase activity GO:0003973
Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
3 A1Z8D3 (/ISS) Q9WU19 (/ISS) Q9WU19 (/ISS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
3 Q9NYQ2 (/ISO) Q9WU19 (/ISO) Q9WU19 (/ISO)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
3 Q9NYQ2 (/ISO) Q9WU19 (/ISO) Q9WU19 (/ISO)
Glycolate oxidase activity GO:0008891
Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide.
2 Q9WU19 (/ISO) Q9WU19 (/ISO)
Glycolate oxidase activity GO:0008891
Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide.
2 Q9WU19 (/ISS) Q9WU19 (/ISS)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
2 Q9WU19 (/ISS) Q9WU19 (/ISS)
Long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity GO:0052853
Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons.
2 Q9NYQ3 (/IDA) Q9NYQ3 (/IDA)
Long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity GO:0052853
Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons.
1 Q9NYQ2 (/ISO)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
6 Q9NYQ3 (/TAS) Q9NYQ3 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS)
Fatty acid alpha-oxidation GO:0001561
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
4 Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA)
Cellular nitrogen compound metabolic process GO:0034641
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
4 Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS)
Glycolate catabolic process GO:0046296
The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
4 Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA)
Fatty acid alpha-oxidation GO:0001561
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
2 Q9WU19 (/ISO) Q9WU19 (/ISO)
Fatty acid alpha-oxidation GO:0001561
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
2 Q9WU19 (/ISS) Q9WU19 (/ISS)
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
2 Q9NYQ3 (/TAS) Q9NYQ3 (/TAS)
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
2 Q9NYQ3 (/IDA) Q9NYQ3 (/IDA)
Glycolate catabolic process GO:0046296
The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
2 Q9WU19 (/ISO) Q9WU19 (/ISO)
Glycolate catabolic process GO:0046296
The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
2 Q9WU19 (/ISS) Q9WU19 (/ISS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 B0BNF9 (/IEP)
Mandelate metabolic process GO:0018924
The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
1 Q07523 (/IDA)
Mandelate metabolic process GO:0018924
The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
1 Q9NYQ2 (/ISO)
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
1 Q9NYQ2 (/ISO)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q07523 (/IDA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9NYQ2 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
9 Q07523 (/IDA) Q9NYQ3 (/IDA) Q9NYQ3 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9UJM8 (/IDA) Q9WU19 (/IDA) Q9WU19 (/IDA)
Peroxisomal matrix GO:0005782
The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.
6 Q9NYQ3 (/TAS) Q9NYQ3 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 Q9NYQ3 (/TAS) Q9NYQ3 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS) Q9UJM8 (/TAS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 Q9NYQ2 (/ISO) Q9WU19 (/ISO) Q9WU19 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9NYQ2 (/HDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 A1Z8D3 (/ISM)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 A1Z8D3 (/ISS)