The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Fructose-bisphosphate aldolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 34 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
22 P00883 (/IDA) P00884 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P05062 (/IDA) P05062 (/IDA) P05064 (/IDA) P05064 (/IDA)
(12 more)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
14 A5A6I5 (/ISS) P05063 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05065 (/ISS) P09117 (/ISS) P53448 (/ISS) Q5NVR5 (/ISS)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 P00883 (/IPI) P04075 (/IPI) P04075 (/IPI) P04075 (/IPI) P04075 (/IPI) P05062 (/IPI) P05062 (/IPI) P05065 (/IPI) P09117 (/IPI) P09972 (/IPI)
(3 more)
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
10 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P05062 (/IDA) P05062 (/IDA) P09972 (/IDA) P09972 (/IDA) P09972 (/IDA) P09972 (/IDA)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
7 P00883 (/IMP) P05064 (/IMP) P05064 (/IMP) P05064 (/IMP) P05064 (/IMP) Q91Y97 (/IMP) Q91Y97 (/IMP)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
7 P05063 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
7 P05063 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
6 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
4 P05064 (/IPI) P05064 (/IPI) P05064 (/IPI) P05064 (/IPI)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
4 P05064 (/IGI) P05064 (/IGI) P05064 (/IGI) P05064 (/IGI)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
4 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
4 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 P05062 (/IPI) P05062 (/IPI) P54216 (/IPI)
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
2 P05062 (/IDA) P05062 (/IDA)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Fructose-1-phosphate aldolase activity GO:0061609
Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
2 P05062 (/IDA) P05062 (/IDA)
Fructose-1-phosphate aldolase activity GO:0061609
Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
2 Q91Y97 (/IMP) Q91Y97 (/IMP)
Fructose-1-phosphate aldolase activity GO:0061609
Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
2 P05062 (/IMP) P05062 (/IMP)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
1 P07341 (/ISA)
Fructose-bisphosphate aldolase activity GO:0004332
Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
1 P05063 (/NAS)
MAP kinase activity GO:0004707
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
1 Q9DGE3 (/ISS)
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
1 P07341 (/ISA)
Phosphatidylcholine binding GO:0031210
Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
1 P00884 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P07341 (/ISA)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 P07341 (/ISA)
Fructose-1-phosphate aldolase activity GO:0061609
Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
1 P07341 (/ISA)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
1 P07341 (/ISA)

There are 92 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
11 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P05062 (/TAS) P05062 (/TAS) P07341 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
(1 more)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
11 A5A6I5 (/ISS) P04075 (/ISS) P04075 (/ISS) P04075 (/ISS) P04075 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05065 (/ISS)
(1 more)
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
10 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P05062 (/IDA) P05062 (/IDA) P09972 (/IDA) P09972 (/IDA) P09972 (/IDA) P09972 (/IDA)
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
10 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P05062 (/TAS) P05062 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
8 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
7 A5A6I5 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05064 (/ISS) P05065 (/ISS) Q5NVR5 (/ISS)
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
7 P05063 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
7 P05063 (/ISS) P09117 (/ISS) P53448 (/ISS) Q5R1X4 (/ISS) Q9GKW3 (/ISS) Q9GKW3 (/ISS) Q9GKW3 (/ISS)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
6 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P05062 (/IMP) P05062 (/IMP)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
6 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
6 P00883 (/IDA) P00884 (/IDA) P05062 (/IDA) P05062 (/IDA) P07764 (/IDA) P07764 (/IDA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
6 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Glycolytic process through fructose-6-phosphate GO:0061615
The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
6 P05064 (/IC) P05064 (/IC) P05064 (/IC) P05064 (/IC) Q91Y97 (/IC) Q91Y97 (/IC)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
4 P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
4 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
4 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Striated muscle contraction GO:0006941
A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
4 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP)
Striated muscle contraction GO:0006941
A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
4 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Methylglyoxal biosynthetic process GO:0019242
The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
4 P05064 (/IMP) P05064 (/IMP) P05064 (/IMP) P05064 (/IMP)
Epithelial cell differentiation GO:0030855
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
4 P09972 (/IEP) P09972 (/IEP) P09972 (/IEP) P09972 (/IEP)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
4 P04075 (/IMP) P04075 (/IMP) P04075 (/IMP) P04075 (/IMP)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
3 A0A060WV84 (/IDA) A0A060WV84 (/IDA) A0A060XHN5 (/IDA)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P05065 (/IEP) P09117 (/IEP)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
2 Q803Q7 (/IMP) Q8JH72 (/IMP)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
2 P00884 (/IEP) P07341 (/IEP)
Thigmotaxis GO:0001966
The directed movement of a motile cell or organism in response to touch.
2 Q803Q7 (/IMP) Q8JH72 (/IMP)
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
2 P05062 (/IDA) P05062 (/IDA)
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 Q803Q7 (/IMP) Q8JH72 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 Q803Q7 (/IMP) Q8JH72 (/IMP)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
2 P07764 (/NAS) P07764 (/NAS)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 P00884 (/IEP) P09117 (/IEP)
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
2 P05062 (/IGI) P05062 (/IGI)
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
2 P07764 (/IMP) P07764 (/IMP)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
2 Q803Q7 (/IMP) Q8JH72 (/IMP)
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
2 Q91Y97 (/IC) Q91Y97 (/IC)
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
2 P05062 (/TAS) P05062 (/TAS)
Glycolytic process through fructose-1-phosphate GO:0061625
The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.
2 Q91Y97 (/IC) Q91Y97 (/IC)
Vacuolar proton-transporting V-type ATPase complex assembly GO:0070072
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
2 P05062 (/IGI) P05062 (/IGI)
Vacuolar proton-transporting V-type ATPase complex assembly GO:0070072
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Fructose metabolic process GO:0006000
The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 P07341 (/ISA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 P07341 (/ISA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 P54216 (/NAS)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 P07341 (/TAS)
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
1 P07341 (/ISA)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P09117 (/IMP)
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
1 P05063 (/ISO)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P09117 (/IDA)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P05063 (/ISO)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P05065 (/IEP)
Response to carbohydrate GO:0009743
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
1 P00884 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 P00884 (/IEP)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
1 P00884 (/IDA)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 P09117 (/IEP)
Methylglyoxal biosynthetic process GO:0019242
The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
1 P05065 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 P00883 (/IDA)
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
1 P07341 (/ISA)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
1 P09117 (/IEP)
Cellular response to extracellular stimulus GO:0031668
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
1 P00884 (/IEP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P05065 (/IEP)
Positive regulation of ATPase activity GO:0032781
Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
1 P07341 (/ISA)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P00884 (/IEP)
Negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
1 P00883 (/IMP)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
1 P05065 (/IEP)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q9DGE3 (/ISS)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P00884 (/IEP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 P00884 (/IEP)
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 P00884 (/IEP)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P00884 (/IDA)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P05065 (/IEP)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 P00884 (/IEP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 P09117 (/IDA)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 P00883 (/IPI)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 P05063 (/ISO)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
1 P09117 (/IPI)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
1 P05063 (/ISO)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 P00884 (/IEP)
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 P00884 (/IEP)
Vacuolar proton-transporting V-type ATPase complex assembly GO:0070072
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
1 P07341 (/ISA)
Response to interleukin-6 GO:0070741
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
1 P00884 (/IEP)

There are 64 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 H3BQN4 (/IDA) H3BQN4 (/IDA) J3KPS3 (/IDA) J3KPS3 (/IDA) P00884 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) V9HWN7 (/IDA)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P05062 (/TAS) P05062 (/TAS) P07341 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
(1 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
10 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P05062 (/HDA) P05062 (/HDA) P09972 (/HDA) P09972 (/HDA) P09972 (/HDA) P09972 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
8 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P05064 (/HDA) P05064 (/HDA) P05064 (/HDA) P05064 (/HDA)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
8 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Tertiary granule lumen GO:1904724
Any membrane-enclosed lumen that is part of a tertiary granule.
8 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
8 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS) P09972 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P00884 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05065 (/IDA) P09117 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P05063 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) Q91Y97 (/ISO) Q91Y97 (/ISO)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
6 P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P07764 (/IDA) P07764 (/IDA)
Sperm fibrous sheath GO:0035686
A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.
6 A6ZI46 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) Q9CPQ9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P00884 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
4 P09972 (/IC) P09972 (/IC) P09972 (/IC) P09972 (/IC)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
4 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 P04075 (/HDA) P04075 (/HDA) P04075 (/HDA) P04075 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA)
Platelet alpha granule lumen GO:0031093
The volume enclosed by the membrane of the platelet alpha granule.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
I band GO:0031674
A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
4 P04075 (/TAS) P04075 (/TAS) P04075 (/TAS) P04075 (/TAS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
4 P05064 (/IDA) P05064 (/IDA) P05064 (/IDA) P05064 (/IDA)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
4 P05064 (/HDA) P05064 (/HDA) P05064 (/HDA) P05064 (/HDA)
Sperm head GO:0061827
The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.
4 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA)
Sperm head GO:0061827
The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 P04075 (/IDA) P04075 (/IDA) P04075 (/IDA) P04075 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 P05064 (/ISO) P05064 (/ISO) P05064 (/ISO) P05064 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
2 P05062 (/IDA) P05062 (/IDA)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P07764 (/HDA) P07764 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Rough endoplasmic reticulum membrane GO:0030867
The lipid bilayer surrounding the rough endoplasmic reticulum.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Smooth endoplasmic reticulum membrane GO:0030868
The lipid bilayer surrounding the smooth endoplasmic reticulum.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
M band GO:0031430
The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.
2 P07764 (/IDA) P07764 (/IDA)
Centriolar satellite GO:0034451
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.
2 P05062 (/IDA) P05062 (/IDA)
Centriolar satellite GO:0034451
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q91Y97 (/ISO) Q91Y97 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P00884 (/IDA)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
1 P05065 (/IDA)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
1 P54216 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P54216 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P05063 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P05065 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 P00884 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 P54216 (/HDA)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
1 P07341 (/ISA)
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 P54216 (/HDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P09117 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 P05063 (/ISO)
Rough endoplasmic reticulum membrane GO:0030867
The lipid bilayer surrounding the rough endoplasmic reticulum.
1 P00884 (/IDA)
Smooth endoplasmic reticulum membrane GO:0030868
The lipid bilayer surrounding the smooth endoplasmic reticulum.
1 P00884 (/IDA)
Centriolar satellite GO:0034451
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.
1 P07341 (/ISA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P00884 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 P00884 (/IDA)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
1 P54216 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P07341 (/ISA)
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
1 P09117 (/IDA)
Postsynaptic cytosol GO:0099524
The region of the cytosol consisting of all cytosol that is part of the postsynapse.
1 P05063 (/ISO)