The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldolase class I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: Triosephosphate isomerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
34 Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA) Q07412 (/IDA)
(24 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
17 Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI) Q07412 (/IPI)
(7 more)
Triose-phosphate isomerase activity GO:0004807
Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
5 Q81X76 (/ISS) Q81X76 (/ISS) Q81X76 (/ISS) Q81X76 (/ISS) Q81X76 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
22 Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS)
(12 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
17 Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS)
(7 more)
Pentose-phosphate shunt GO:0006098
The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
17 Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS)
(7 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
17 Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS) Q7KQM0 (/ISS)
(7 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q59182 (/IDA) Q59182 (/IDA) Q59182 (/IDA)