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CATH Superfamily 3.20.20.60

Phosphoenolpyruvate-binding domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphoenolpyruvate-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: 3-methyl-2-oxobutanoate hydroxymethyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-methyl-2-oxobutanoate hydroxymethyltransferase activity GO:0003864
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
 35 P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA)
(25 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
 34 P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA)
(24 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 26 P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA)
(16 more)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity GO:0003864
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
 9 Q09672 (/ISS) Q54LH3 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity GO:0003864
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
 2 O82357 (/IGI) Q9M315 (/IGI)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity GO:0003864
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
 1 P38122 (/IMP)
3-methyl-2-oxobutanoate hydroxymethyltransferase activity GO:0003864
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
 1 Q9Y7B6 (/RCA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 1 Q9M315 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
 1 Q9M315 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
 27 P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP)
(17 more)
Pantothenate biosynthetic process from valine GO:0033317
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including valine.
 26 P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP) P31057 (/IMP)
(16 more)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
 9 P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) P9WIL7 (/IDA) Q9Y7B6 (/IDA)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
 9 Q09672 (/ISS) Q54LH3 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS) Q9KUD0 (/ISS)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
 2 O82357 (/IGI) Q9M315 (/IGI)
Coenzyme biosynthetic process GO:0009108
The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
 1 Q9Y7B6 (/RCA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 26 P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA)
(16 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 26 P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA) P31057 (/IDA)
(16 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 26 P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA) P31057 (/HDA)
(16 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 8 P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA) P9WIL7 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
 3 O82357 (/IDA) P38122 (/IDA) Q9M315 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
 2 P38122 (/HDA) Q09672 (/HDA)