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CATH Superfamily 3.20.20.480

Trimethylamine methyltransferase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Trimethylamine methyltransferase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Trimethylamine methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Trimethylamine--corrinoid protein] Co-methyltransferase. [EC: 2.1.1.250]
Trimethylamine + a [Co(I) trimethylamine-specific corrinoid protein] = a [methyl-Co(III) trimethylamine-specific corrinoid protein] + dimethylamine.
  • The enzyme, which catalyzes the transfer of a methyl group from trimethylamine to a trimethylamine-specific corrinoid protein (MttC), is involved in methanogenesis from trimethylamine.
  • The enzyme contains the unusual amino acid pyrrolysine.
  • Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state.
  • During methylation the cobalt is oxidized to the Co(III) state.
  • The methylated corrinoid protein is substrate for EC 2.1.1.247.
 30 A0A0E3LQK6 A0A0E3LQK6 A0A0E3LQK6 A0A0E3LQK6 A0A0E3Q0Z2 A0A0E3Q0Z2 A0A0E3Q0Z2 A0A0E3QQH4 A0A0E3QQH4 A0A0E3QRM4
(20 more...)