The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homocysteine-binding-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Homocysteine S-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
S-adenosylmethionine-homocysteine S-methyltransferase activity GO:0008898
Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.
19 A4ZGQ8 (/IDA) A4ZGQ8 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA)
(9 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
15 Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA) Q47690 (/IDA)
(5 more)
Selenocysteine methyltransferase activity GO:0016205
Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.
1 Q4VNK0 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
15 Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP) Q47690 (/IEP)
(5 more)
S-methylmethionine metabolic process GO:0033477
The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.
15 Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP) Q47690 (/IMP)
(5 more)
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
3 A4ZGQ8 (/IDA) A4ZGQ8 (/IDA) Q4VNK0 (/IDA)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
2 Q9M1W4 (/IDA) Q9SDL7 (/IDA)
Response to selenium ion GO:0010269
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.
1 Q4VNK0 (/IDA)
S-methylmethionine cycle GO:0033528
A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.
1 Q9M1W4 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8LAX0 (/IDA)