The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CBS-domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 41: Cystathionine beta-synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cystathionine beta-synthase activity GO:0004122
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
1 B2LXT5 (/IMP)
Cystathionine beta-synthase activity GO:0004122
Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
1 B2LXT5 (/RCA)
Cysteine synthase activity GO:0004124
Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
1 B2LXT5 (/RCA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 B2LXT5 (/RCA)
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
1 B2LXT5 (/IGI)
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
1 B2LXT5 (/IMP)
Cysteine metabolic process GO:0006534
The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
1 B2LXT5 (/RCA)
L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine GO:0019280
The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.
1 B2LXT5 (/IMP)
Cysteine biosynthetic process via cystathionine GO:0019343
The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.
1 B2LXT5 (/IMP)
Transsulfuration GO:0019346
The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
1 B2LXT5 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.