The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Dynein heavy chain 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP-dependent microtubule motor activity, minus-end-directed GO:0008569
Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
4 A0A0U1RVI8 (/ISS) Q5LJP0 (/ISS) Q9GPN8 (/ISS) Q9VZ77 (/ISS)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
3 A0A0U1RVI8 (/ISS) Q5LJP0 (/ISS) Q9GPN8 (/ISS)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
3 A0A0U1RVI8 (/TAS) Q5LJP0 (/TAS) Q9GPN8 (/TAS)
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
2 Q386I6 (/ISM) Q57YY8 (/ISM)
Dynein light chain binding GO:0045503
Interacting selectively and non-covalently with a light chain of the dynein complex.
1 A8I5C3 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cilium movement GO:0003341
The directed, self-propelled movement of a cilium.
4 A0A0U1RVI8 (/ISS) Q5LJP0 (/ISS) Q9GPN8 (/ISS) Q9VZ77 (/ISS)
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
2 Q386I6 (/ISM) Q57YY8 (/ISM)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
1 Q9VZ77 (/IMP)
Sperm competition GO:0046692
Any process that contributes to the success of sperm fertilization in multiply-mated females.
1 Q9VZ77 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inner dynein arm GO:0036156
Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
4 A0A0U1RVI8 (/ISS) Q5LJP0 (/ISS) Q9GPN8 (/ISS) Q9VZ77 (/ISS)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
3 Q4Q8K9 (/ISO) Q4QB21 (/ISO) Q4QFY9 (/ISO)
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
3 A0A0U1RVI8 (/TAS) Q5LJP0 (/TAS) Q9GPN8 (/TAS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
2 Q386I6 (/IDA) Q57YY8 (/IDA)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
2 Q386I6 (/IDA) Q57YY8 (/IDA)
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
2 Q386I6 (/ISM) Q57YY8 (/ISM)