The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 59: Microtubule-associated proteins 1A/1B light chain ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
97 Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI) Q6XVN8 (/IPI)
(87 more)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
42 Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI) Q9GZQ8 (/IPI)
(32 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
27 Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA)
(17 more)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
27 Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA)
(17 more)
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
2 Q2HJ23 (/ISS) Q2HJ23 (/ISS)
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
2 Q2HJ23 (/ISS) Q2HJ23 (/ISS)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
1 Q62625 (/IDA)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
1 Q62625 (/IDA)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
1 Q9CQV6 (/ISO)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q62625 (/IPI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q9CQV6 (/ISO)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
63 O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) Q2HJ23 (/ISS) Q2HJ23 (/ISS) Q91VR7 (/ISS)
(53 more)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
43 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(33 more)
Autophagy of mitochondrion GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
42 Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI) Q9GZQ8 (/IGI)
(32 more)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
42 Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA)
(32 more)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
42 Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA)
(32 more)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
42 Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS)
(32 more)
Autophagosome maturation GO:0097352
Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.
42 Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA)
(32 more)
Autophagosome maturation GO:0097352
Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.
42 Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS)
(32 more)
Autophagy of mitochondrion GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Autophagosome maturation GO:0097352
Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
27 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(17 more)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
27 Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP) Q9H492 (/IMP)
(17 more)
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Response to iron(II) ion GO:0010040
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Response to lead ion GO:0010288
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Cellular response to amino acid starvation GO:0034198
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Response to morphine GO:0043278
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
27 Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP) Q6XVN8 (/IEP)
(17 more)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q62625 (/IDA)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q9CQV6 (/ISO)
Positive regulation of mucus secretion GO:0070257
Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
1 Q9CQV6 (/IMP)

There are 38 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
97 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(87 more)
Autophagosome membrane GO:0000421
The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
55 Q62625 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(45 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
55 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(45 more)
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
54 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(44 more)
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
51 O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) Q2HJ23 (/ISS) Q2HJ23 (/ISS) Q91VR7 (/ISS)
(41 more)
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
51 O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) Q2HJ23 (/ISS) Q2HJ23 (/ISS) Q91VR7 (/ISS)
(41 more)
Autophagosome membrane GO:0000421
The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
42 Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS)
(32 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
42 Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS) Q9GZQ8 (/TAS)
(32 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
34 O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) Q91VR7 (/ISS) Q91VR7 (/ISS) Q91VR7 (/ISS)
(24 more)
Autophagosome membrane GO:0000421
The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
28 Q62625 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(18 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
28 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(18 more)
Autolysosome GO:0044754
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
28 Q9CQV6 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA) Q9H492 (/IDA)
(18 more)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
27 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(17 more)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Organelle membrane GO:0031090
A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Autolysosome GO:0044754
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
27 Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP) Q6XVN8 (/EXP)
(17 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
27 Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA) Q6XVN8 (/IDA)
(17 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
27 Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO) Q91VR7 (/ISO)
(17 more)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
22 O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) O41515 (/ISS) Q9GZQ8 (/ISS) Q9GZQ8 (/ISS) Q9GZQ8 (/ISS)
(12 more)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
15 Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA)
(5 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
15 Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA) Q9GZQ8 (/IDA)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q2HJ23 (/ISS) Q2HJ23 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CQV6 (/ISO)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 Q62625 (/IDA)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 Q9CQV6 (/ISO)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 Q9CQV6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9CQV6 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q62625 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q9CQV6 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q62625 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q9CQV6 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q62625 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q9CQV6 (/ISO)