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CATH Superfamily 3.10.20.30

Beta-grasp domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24: Na(+)-translocating NADH-quinone reductase subunit...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
 18 A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) Q56584 (/IDA) Q56584 (/IDA)
(8 more)
FAD binding GO:0071949
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
 18 A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) Q56584 (/IDA) Q56584 (/IDA)
(8 more)
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
 10 Q8EHV4 (/ISS) Q8EID5 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
 10 Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS) Q56584 (/ISS)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
 8 A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
 18 A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) Q56584 (/IDA) Q56584 (/IDA)
(8 more)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 8 A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA) A5F5Y4 (/IDA)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
 2 Q8EHV4 (/ISS) Q8EID5 (/ISS)
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 2 Q8EHV4 (/ISS) Q8EID5 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH dehydrogenase complex GO:0030964
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
 8 Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS) Q9X4Q8 (/ISS)