The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: GTP pyrophosphokinase (RelA/SpoT)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP diphosphokinase activity GO:0008728
Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
150 P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA)
(140 more)
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity GO:0008893
Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.
144 P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA)
(134 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
143 F4JHA2 (/IPI) F4JHA2 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI) P0AG24 (/IPI)
(133 more)
GTP diphosphokinase activity GO:0008728
Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
4 Q3ZAI9 (/ISS) Q3ZAI9 (/ISS) Q74AW3 (/ISS) Q74AW3 (/ISS)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
3 P9WHG9 (/IDA) P9WHG9 (/IDA) P9WHG9 (/IDA)
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity GO:0008893
Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.
2 F4JHA2 (/IGI) F4JHA2 (/IGI)
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity GO:0008893
Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.
2 F4JHA2 (/IMP) F4JHA2 (/IMP)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
147 P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA) P0AG20 (/IDA)
(137 more)
Guanosine tetraphosphate metabolic process GO:0015969
The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
147 P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP) P0AG20 (/IMP)
(137 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
141 P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP) P0AG24 (/IMP)
(131 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
14 P9WHG9 (/IMP) P9WHG9 (/IMP) P9WHG9 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP)
(4 more)
Stringent response GO:0015968
A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.
14 P9WHG9 (/IMP) P9WHG9 (/IMP) P9WHG9 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP) Q9I524 (/IMP)
(4 more)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
9 Q9KNM2 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS) Q9S3S3 (/ISS)
Guanosine tetraphosphate biosynthetic process GO:0015970
The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
6 P52560 (/IMP) P52560 (/IMP) P52560 (/IMP) P52560 (/IMP) P52560 (/IMP) P52560 (/IMP)
Stringent response GO:0015968
A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.
4 Q3ZAI9 (/ISS) Q3ZAI9 (/ISS) Q74AW3 (/ISS) Q74AW3 (/ISS)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 F4JHA2 (/IEP) F4JHA2 (/IEP)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
2 F4JHA2 (/IMP) F4JHA2 (/IMP)
Photosynthesis GO:0015979
The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
2 F4JHA2 (/IDA) F4JHA2 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
141 P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA) P0AG24 (/IDA)
(131 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
3 P9WHG9 (/HDA) P9WHG9 (/HDA) P9WHG9 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P9WHG9 (/HDA) P9WHG9 (/HDA) P9WHG9 (/HDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 F4JHA2 (/IDA) F4JHA2 (/IDA)