The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome b5-like heme/steroid binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Fatty acid 2-hydroxylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid alpha-hydroxylase activity GO:0080132
Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
4 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS)
Fatty acid alpha-hydroxylase activity GO:0080132
Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
2 Q5MPP0 (/IDA) Q7L5A8 (/IDA)
Fatty acid alpha-hydroxylase activity GO:0080132
Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
2 Q2LAM0 (/IMP) Q7L5A8 (/IMP)
Fatty acid alpha-hydroxylase activity GO:0080132
Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
1 Q5MPP0 (/ISO)
Fatty acid alpha-hydroxylase activity GO:0080132
Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
1 Q7L5A8 (/TAS)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucosylceramide biosynthetic process GO:0006679
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q7L5A8 (/ISS)
Galactosylceramide biosynthetic process GO:0006682
The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q7L5A8 (/ISS)
Plasma membrane raft organization GO:0044857
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q7L5A8 (/ISS)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q5MPP0 (/ISS)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q5MPP0 (/ISS)
Galactosylceramide biosynthetic process GO:0006682
The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
2 Q2LAM0 (/IMP) Q5MPP0 (/IMP)
Sebaceous gland cell differentiation GO:0001949
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
1 Q5MPP0 (/IMP)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
1 Q5MPP0 (/IDA)
Glucosylceramide biosynthetic process GO:0006679
The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
1 Q5MPP0 (/IMP)
Galactosylceramide biosynthetic process GO:0006682
The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
1 Q5MPP0 (/IDA)
Galactosylceramide biosynthetic process GO:0006682
The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
1 Q5MPP0 (/ISO)
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
1 Q7L5A8 (/TAS)
Lipid modification GO:0030258
The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.
1 Q5MPP0 (/IDA)
Lipid modification GO:0030258
The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.
1 Q5MPP0 (/IMP)
Central nervous system myelin maintenance GO:0032286
The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
1 Q5MPP0 (/IMP)
Peripheral nervous system myelin maintenance GO:0032287
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
1 Q5MPP0 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q5MPP0 (/IMP)
Regulation of hair cycle GO:0042634
Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
1 Q5MPP0 (/IMP)
Plasma membrane raft organization GO:0044857
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.
1 Q5MPP0 (/IMP)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
1 Q7L5A8 (/IDA)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
1 Q5MPP0 (/IMP)
Ceramide biosynthetic process GO:0046513
The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
1 Q5MPP0 (/ISO)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
1 Q7L5A8 (/IMP)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
1 Q5MPP0 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 Q2LAM0 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q4R4P4 (/ISS) Q5MPP0 (/ISS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q5MPP0 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q7L5A8 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q7L5A8 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q5MPP0 (/ISO)